Lipid

An increase in insulin sensitivity from a plant-based vegan diet led to a decrease in liver fat and a mean weight loss of 6.4 kg in a cohort of adults with overweight and obesity, according to findings published in JAMA Network Open.

In this video, Jeffrey A. Sparks, MD, MMSc, associate physician at Brigham and Women's Hospital, spoke with Healio about a cross-sectional study presented at ACR 2020 that delved into the “lipid paradox.”

Three machine learning approaches outperformed the Dutch Lipid Score to diagnose patients with genetic mutations that cause familial hypercholesterolemia, according to a study published in the European Journal of Preventive Cardiology.

Women in early menopause who received oral estradiol treatment had a reduced progression of lipid deposition in the carotid arterial wall compared with placebo, according to a secondary analysis of the ELITE trial presented at the American Heart Association Epidemiology, Prevention, Lifestyle and Cardiometabolic Health Scientific Sessions.

Adolescents with obesity assigned the weekly GLP-1 receptor agonist exenatide for 6 months experienced a modest reduction in BMI along with improvements in several cardiometabolic markers, including 2-hour glucose and lipid profile, according to findings published in Pediatric Obesity.

Obesity may affect a clinician’s ability to correctly interpret 24 routine blood tests for children, including liver function tests, inflammation markers, lipids and iron levels, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Patients with familial hypercholesterolemia who were treated in U.S. specialty clinics had a harder time achieving LDL less than 100 mg/dL than those who had atherosclerotic CVD at the start of lipid-lowering therapy.

In its 14th year, the Cardiometabolic Health Congress, taking place in Chicago from Oct. 10 to 13, will feature an extensive agenda including an innovative preconference summit, a broad variety of session topics, numerous advanced learning workshops and a faculty panel consisting of many of cardiometabolic medicine’s foremost clinical experts.

A CV risk-based strategy for BP-lowering has the potential to prevent more CVD events than previous and current guidelines, while aligning with current lipid-lowering recommendations and retaining comparable efficacy.