Limb Salvage

Compared with placebo, a preoperative and intraoperative infusion of tranexamic acid was associated with significant reductions in perioperative blood loss and transfusions during pediatric limb-salvage surgery for bone cancer.

A 56-year-old man presented to the ED with 3 months of atraumatic left thigh pain.

SAN FRANCISCO — Results showed use of local antibiotic-loaded hydroxyapatite and calcium sulfate biocomposite void filler may increase limb salvage and ulcer healing rates among patients with diabetic foot infections and vascular disease.

Compared with white patients, Black and Hispanic patients with peripheral vascular disease are younger, have more comorbidities, are less likely to undergo revascularization and more likely to undergo amputation, national data show.

LAS VEGAS — Results presented at the American Academy of Orthopaedic Surgeons Annual Meeting showed the use of megaprosthesis for non-oncologic limb salvage yielded significant complication risk and an elevated revision rate at 5 years.

Compared with endovascular therapy, thromboendarterectomy surgery was associated with better 1-year patency, but longer hospital stays, in patients undergoing revascularization for common femoral artery lesions, researchers reported.

The Society for Cardiovascular Angiography and Interventions published a position statement that details key skills needed by all endovascular specialists who care for patients with chronic limb-threatening ischemia.

A novel, interdisciplinary limb salvage team reevaluating severe cases of critical limb ischemia avoided amputation for 75% of patients 180 days after revascularization, according to findings from a small study.

SAN DIEGO — After wide resection of lower extremity osteosarcoma, use of a silver-coated megaprostheses for reconstruction may be cost-effective at mitigating prosthetic joint infections vs. use of standard implants, according to results.

Antibiotic, calcium sulfate-coated intramedullary nails are safe and “100% effective” for long bone infection prophylaxis and could be comparable to polymethylmethacrylate antibiotic-coated nails, according to a presenter.