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Leukemia

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December 07, 2020
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IDH mutations linked to cardiotoxicity among adults with AML


  <i>IDH</i> mutations linked to cardiotoxicity among adults with AML

Adults with acute myeloid leukemia with IDH mutations appeared to be at increased risk for coronary artery disease and exacerbated cardiotoxicity during treatment with anthracyclines, according to study results.

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December 04, 2020
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Black race an independent predictor of poor survival among young adults with AML

Black race an independent predictor of poor survival among young adults with AML

Black young adults with favorable molecular-risk acute myeloid leukemia had poorer survival outcomes than their white counterparts, according to study results presented at the virtual ASH Annual Meeting and Exposition.

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December 03, 2020
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TKI discontinuation safe for certain patients with chronic myeloid leukemia

TKI discontinuation safe for certain patients with chronic myeloid leukemia

Discontinuation of tyrosine kinase inhibitors after 3 years of use appeared safe for adults with chronic myeloid leukemia who achieved a sustained deep molecular response, according to results of the LAST study published in JAMA Oncology.

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December 01, 2020
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Combination reduces relapse incidence after allogeneic HSCT in high-risk AML subset

Combination reduces relapse incidence after allogeneic HSCT in high-risk AML subset

Recombinant human granulocyte colony-stimulating factor combined with minimal-dose decitabine appeared to reduce relapse incidence after allogeneic transplant among patients with high-risk acute myeloid leukemia, study results showed.

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November 29, 2020
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MD Anderson names Andrew Sabin Family Fellows

MD Anderson names Andrew Sabin Family Fellows

The University of Texas MD Anderson named 10 early-career faculty members to its fifth annual class of Andrew Sabin Family Fellows.

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November 25, 2020
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A decade of success: CAR-T pioneers reflect on past, look toward future

Ten years ago, researchers at NCI reported use of CD19-directed chimeric antigen receptor T-cell therapy that successfully induced remission in a patient with follicular lymphoma.

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November 24, 2020
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Prognostic model identifies patients with CLL at risk for ibrutinib failure

Prognostic model identifies patients with CLL at risk for ibrutinib failure

A four-factor prognostic model identified patients with chronic lymphocytic leukemia who had poorer survival outcomes with ibrutinib, according to study results published in Journal of Clinical Oncology.

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November 12, 2020
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NIH grant to fund study of ‘chemo brain’ among children

NIH grant to fund study of &lsquo;chemo brain&rsquo; among children

So-called “chemo brain” is a functionally limiting and frustrating consequence of curative treatment for cancer.

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November 07, 2020
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ASH announces four new executive committee members

ASH announces four new executive committee members

ASH announced the election of four new members to its executive committee.

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November 04, 2020
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Three-drug combination induces deep remission in treatment-naive, relapsed/refractory CLL

Three-drug combination induces deep remission in treatment-naive, relapsed/refractory CLL

A combination of obinutuzumab, ibrutinib and venetoclax induced deep remissions in patients with treatment-naive or relapsed/refractory chronic lymphocytic leukemia, according to study results published in Journal of Clinical Oncology.

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