Leukemia
NCCN Foundation presents awards to young investigators
FDA grants orphan drug designation to CA-4948 for AML, myelodysplastic syndrome
The FDA granted orphan drug designation to CA-4948 for treatment of acute myeloid leukemia and myelodysplastic syndrome, according to the agent’s manufacturer.
Disruption in DNA repair rhythms may explain higher cancer risk among night-shift workers
Working night shifts may interfere with natural 24-hour rhythms in the activity of certain genes related to cancer, leading to increased cancer risk, according to a study published in the Journal of Pineal Research.
Kite submits supplemental BLA for Tecartus to treat advanced ALL
Kite Pharma submitted a supplemental biologics license application to the FDA for brexucabtagene autoleucel to treat adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia, according to the agent’s manufacturer.
Diet, exercise regimen improves efficacy of chemotherapy in youth with leukemia
Caloric restriction through diet and exercise appeared to enhance the efficacy of chemotherapy among young patients with B-cell acute lymphoblastic leukemia, according to results of the IDEAL study published in Blood Advances.
FDA approves Vyxeos for secondary acute myeloid leukemia in children
The FDA expanded the approval of daunorubicin and cytarabine to include the treatment of children aged at least 1 year with newly diagnosed therapy-related acute myeloid leukemia, according to a manufacturer-issued press release.
Administering CAR T-cell therapy to younger patients requires ‘ongoing and open’ relationships
Although chimeric antigen receptor T-cell therapies are being administered more frequently, they are still available only at a limited number of specialized centers.
ASH awards support resumption of hematologic research paused by pandemic
ASH awarded funding to 19 early-career investigators to support resumption of research paused due to the COVID-19 pandemic.
Whole-genome sequencing simplifies workup of AML, myelodysplastic syndrome
Whole-genome sequencing appeared as accurate as and more efficient than conventional cytogenetic tests for genomic profiling of acute myeloid leukemia and myelodysplastic syndrome, according to data in The New England Journal of Medicine.
Survey: One-third of people with blood cancer unlikely to get COVID-19 vaccine
Nearly one-third of people diagnosed with blood cancers indicated they either are unlikely to get a COVID-19 vaccine or are unsure about doing so, survey results released today by Leukemia & Lymphoma Society showed.