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Leukemia

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September 29, 2021
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Improving dose optimization in oncology: The sotorasib example

Improving dose optimization in oncology: The sotorasib example

Until the last decade, efforts to develop a therapy that successfully targeted the KRAS mutation had been futile.

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September 26, 2021
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9 important updates in blood cancer treatment, research

9 important updates in blood cancer treatment, research

September is Blood Cancer Awareness Month.

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September 23, 2021
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Data support third COVID-19 vaccine dose for some patients with cancer

Data support third COVID-19 vaccine dose for some patients with cancer

COVID-19 variants pose a greater threat to certain patients with cancer, particularly those with hematologic malignancies, confirming the need to promote vaccination within this population, according to data presented at ESMO Congress 2021.

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September 17, 2021
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FDA clears IND application for CRISPR-edited T-cell receptor therapy to treat AML

FDA clears IND application for CRISPR-edited T-cell receptor therapy to treat AML

The FDA cleared an investigational new drug application for NTLA-5001, a T-cell receptor T-cell therapy designed to treat adults with relapsed or refractory acute myeloid leukemia.

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September 16, 2021
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FDA grants fast track designation to CRISPR-edited stem cell therapy for AML

FDA grants fast track designation to CRISPR-edited stem cell therapy for AML

The FDA granted fast track designation to VOR33, an engineered allogeneic stem cell therapy for the treatment of patients with acute myeloid leukemia who are at high risk for relapse.

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September 08, 2021
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Researchers use ‘humanized’ CAR T cells to improve treatment durability for patients with ALL

Researchers use ‘humanized’ CAR T cells to improve treatment durability for patients with ALL

The FDA approved the first chimeric antigen receptor therapy in 2017, authorizing tisagenlecleucel for treatment of children or young adults with relapsed or refractory B-cell acute lymphoblastic leukemia.

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September 03, 2021
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Roswell Park appoints CAR T-cell pioneer as new deputy director

Roswell Park appoints CAR T-cell pioneer as new deputy director

Renier Brentjens, MD, PhD, has been appointed deputy director and chair of the department of medicine of Roswell Park Comprehensive Cancer Center.

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August 28, 2021
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ASH names medical faculty development program award recipients

ASH names medical faculty development program award recipients

Lachelle Dawn Weeks, MD, PhD, of Dana-Farber Cancer Institute and Emilio Ramos, MD, PhD, of University of California, San Francisco, received the ASH-Harold Amos Medical Faculty Development Program Award.

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August 17, 2021
4 min read
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Navigation service assists patients in search for cancer clinical trials

Navigation service assists patients in search for cancer clinical trials

A free nurse navigation service helped overcome barriers to clinical trial enrollment for patients with blood cancer, according to study results published in JCO Oncology Practice.

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August 11, 2021
5 min read
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Remission by ’whatever means’: The role of CAR-T, HSCT for younger patients with ALL

Remission by ’whatever means’: The role of CAR-T, HSCT for younger patients with ALL

Clinicians who treat blood cancers often disagree whether chimeric antigen receptor T-cell therapies are a potential replacement for hematopoietic stem cell transplant.

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