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Leukemia

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December 12, 2021
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Age, sex, other factors impact mortality risk among patients with blood cancer, COVID-19

Age, sex, other factors impact mortality risk among patients with blood cancer, COVID-19

Older age, male sex, pre-COVID-19 prognosis of less than 6 months and deferral of ICU care appeared associated with greater risk for mortality among patients with blood cancer and COVID-19, study results showed.

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December 12, 2021
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Most patients with AML, myelodysplastic syndrome seropositive after two COVID vaccine doses

Most patients with AML, myelodysplastic syndrome seropositive after two COVID vaccine doses

A vast majority of patients with acute myeloid leukemia and myelodysplastic syndrome converted to seropositivity after two COVID-19 vaccine doses, according to a study presented at ASH Annual Meeting and Exposition.

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December 12, 2021
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Ivosidenib regimen extends OS, EFS for acute myeloid leukemia subset

Ivosidenib regimen extends OS, EFS for acute myeloid leukemia subset

The addition of ivosidenib to azacitidine improved outcomes for certain patients with acute myeloid leukemia, according to study results presented at ASH Annual Meeting and Exposition.

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December 12, 2021
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Racial disparities persist among young patients with acute lymphoblastic leukemia

Racial disparities persist among young patients with acute lymphoblastic leukemia

Considerable survival gaps exist among young white, Black and Hispanic individuals with acute lymphoblastic leukemia, according to study results presented at ASH Annual Meeting and Exposition.

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December 11, 2021
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Increased trial participation may mitigate survival disparities for Hispanic AYAs with ALL

Increased trial participation may mitigate survival disparities for Hispanic AYAs with ALL

Hispanic individuals appeared considerably underrepresented in a large clinical trial of adolescents and young adults with acute lymphoblastic leukemia, according to study results presented at ASH Annual Meeting and Exposition.

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December 11, 2021
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Conversations about goals of care often occur too late in high-risk AML

Conversations about goals of care often occur too late in high-risk AML

Goals-of-care discussions often occur too late for patients with poor-prognosis, high-risk acute myeloid leukemia, according to study results presented at ASH Annual Meeting and Exposition.

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December 03, 2021
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FDA approves Rituxan plus chemotherapy for pediatric lymphoma, leukemia

The FDA approved rituximab in combination with chemotherapy for several pediatric cancer indications.

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November 30, 2021
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FDA grants orphan drug designation to dual-target CAR-T for B-cell ALL

FDA grants orphan drug designation to dual-target CAR-T for B-cell ALL

The FDA granted orphan drug designation to CT120, a novel chimeric antigen receptor T-cell therapy, for the treatment of B-cell acute lymphoblastic leukemia.

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November 29, 2021
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FDA grants RMAT designation to CRISPR-edited CAR-T for advanced B-cell malignancies

FDA grants RMAT designation to CRISPR-edited CAR-T for advanced B-cell malignancies

The FDA granted regenerative medicine advanced therapy designation to CTX110, a chimeric antigen receptor T-cell therapy in development for treatment of relapsed or refractory B-cell malignancies.

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November 22, 2021
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Quizartinib regimen extends OS for certain patients with acute myeloid leukemia

Quizartinib regimen extends OS for certain patients with acute myeloid leukemia

The addition of quizartinib to chemotherapy extended OS for certain adults with newly diagnosed acute myeloid leukemia, according to topline data released by the agent’s manufacturer.

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