Leukemia

An investigational chimeric antigen receptor T-cell therapy demonstrated successful expansion and antitumor targeting among younger patients with advanced acute myeloid leukemia, results of the phase 1 PLAT-08 trial showed.

The addition of blinatumomab to Interfant-06 chemotherapy appeared safe for infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia, according to data published in The New England Journal of Medicine.

The disparate prevalence of cardiovascular risk factors among adult Black and Hispanic survivors of childhood cancer was comparable to the disparities in the American general population, researchers reported.

The availability of highly effective targeted agents has changed the treatment landscape for chronic lymphocytic leukemia, but key questions about optimal strategies remain, according to a review published in JAMA.

Children with acute lymphoblastic leukemia who resided along the U.S.-Mexico border appeared at higher risk for death than their counterparts in other areas of Texas, according to study results published in Cancer.

Healio | HemOnc Today is excited to announce a new physician leadership structure, which features seven Associate Medical Editors from various subspecialty areas within oncology and hematology.

Kristen M. Hege, MD, is one of those rare individuals who excels at most of her endeavors.

Ponatinib conferred deeper and more durable responses than imatinib in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia who received either agent in combination with reduced-intensity chemotherapy.

Severe inflammation among individuals with acute myeloid leukemia limits their bodies’ ability to kill cancerous blood cells, according to study results.

A phase 1/phase 2 trial of lisocabtagene maraleucel for adults with advanced chronic lymphocytic leukemia or small lymphocytic lymphoma met its primary endpoint, according to the agent’s manufacturer.