Leiden University Medical Center
Oral octreotide associated with better quality of life, work productivity in acromegaly
Adults with acromegaly reported improved quality of life and more work productivity after transitioning from injectable somatostatin receptor ligands to oral octreotide capsules, according to MPOWERED phase 3 trial data.
Gender-affirming hormone therapy may increase VTE risk among transgender women
Gender‐affirming hormone therapy appeared to increase overall procoagulant profiles among transgender women but not transgender men, according to study results published in Journal of Thrombosis and Haemostasis.
Checkpoint inhibitor response, adverse event rate similar regardless of autoimmune disease
Patients’ response to anti-CTLA-4 or anti-PD-1 checkpoint therapy for advanced melanoma, and their incidence of immune-related adverse events of grade 3 or higher, were similar regardless of preexisting autoimmune disease, according to data.
Digital ulcers, Raynaud's, GI issues biggest detriments to QoL in systemic sclerosis
Digital ulcers, Raynaud symptoms and gastrointestinal complications are the biggest contributors to worsening quality of life in patients with systemic sclerosis, according to data published in Rheumatology.