Left Ventricular Function

Empagliflozin reduced CV death or HF hospitalization compared with placebo in patients with HF with preserved ejection fraction, regardless of diabetes status, according to topline results of the EMPEROR-Preserved trial.

A novel cardiac MRI technology greatly reduced the amount of time it takes for a scan, potentially lifting a barrier to use, researchers reported.

Neurohormonal blockade using candesartan and/or metoprolol for women undergoing treatment for early breast cancer was not significantly protective against minor long-term decline in left ventricular ejection fraction, a speaker reported.

Sustained, low-intensity exercise may not be enough to preserve left ventricular mass and diastolic diameter in long-term space travelers, according to a research letter published in Circulation.

Subclinical impairments in left ventricular systolic function were associated with risk for future incident HF among older adults, according to research published in JAMA Cardiology.

Treatment with mavacamten — a first-in-class cardiac myosin inhibitor — improved symptoms, quality of life and functional status compared with placebo in patients with symptomatic, obstructive hypertrophic cardiomyopathy.

Occupational exposures to vehicle exhaust, burning wood, metals and pesticides were linked to abnormal parameters of left ventricular and right ventricular systolic dysfunction in Hispanic and Latino participants, researchers found.

A transcatheter mitral valve repair system (Pascal, Edwards Lifesciences) for treatment of functional or degenerative mitral regurgitation.

In a randomized controlled trial, post-MI B-type natriuretic peptide infusion failed to reduce left ventricular volume or improve LV ejection fraction compared with placebo, researchers reported.

Among patients with subclinical hypothyroidism and acute MI, treatment with levothyroxine demonstrated no significant improvement in left ventricular function compared with placebo, researchers reported.