Ldl Cholesterol

Among 22 pairs of twins, those who were randomly assigned to a vegan diet had improvements in several cardiovascular measures vs. their twin who was assigned to a healthy omnivore diet, according to findings published in JAMA Network Open.

Electronic records data show race, sex, age and comorbidities influence mortality risk for adults with severe hypercholesterolemia and that one in four of these high-risk patients is not prescribed statin therapy.

Statin therapy is a first-line recommendation for all adults with established atherosclerotic cardiovascular disease or at high atherosclerotic CVD risk, yet reports show many patients cannot — or will not — take statins as prescribed.

PHILADELPHIA — Recaticimab, a novel anti-PCSK9 drug, conferred significant LDL reductions at 48 weeks in a cohort of patients with mixed hyperlipidemias already on statin therapy, a speaker reported.

PHILADELPHIA — A novel single-dose CRISPR base-editing infusion for patients with heterozygous familial hypercholesterolemia and advanced CAD reduced serum PCSK9 and lowered LDL by up to 55% in one patient, a speaker reported.

Data from a real-world cohort in Italy show female sex is the only independent variable associated with lower probability of achieving LDL target level for every risk category, regardless of whether the patient is prescribed statin therapy.

The American College of Cardiology, or ACC, launched a quality improvement and education campaign directed at improving low-density lipoprotein screenings and treatment.

Older individuals appeared to derive similar magnitude of LDL lowering and CV risk reduction from statin therapy initiation vs. younger patients, according to data from a large Danish study.