Joint Infections

A proof-of-concept trial revealed that GA2, a second-generation vaccine candidate that uses genetically attenuated malaria parasites, prevented 89% of participants who received it from being infected with malaria.

Treating patients with bone and joint infections with oral antibiotics led to more patients being discharged exclusively on oral antibiotics and shorter hospital stays without increasing rates of treatment failure, researchers found in a study.

Among people who inject drugs, partial-oral antibiotic treatment for bone and joint infections was effective when paired with medical respite and specialized follow-up care, researchers reported.

Patients who received a kidney-pancreas or heart transplant were more likely to be diagnosed with a bone and joint infection compared with other transplant recipients, according to a study in the American Journal of Transplantation.

Joint replacement surgery is common for patients with arthritis or other joint injury and is usually successful in restoring function.

Routinely ordering mycobacterial cultures for patients with periprosthetic joint infections is not cost-effective and testing is not necessary in most cases, according to a study.

Predictors of treatment success in peri-prosthetic joint infections include nonmodifiable factors like the joint where the infection occurred, age of the implant, patient age and comorbidities, and what caused the infection, a study found.

An international, biospecimen registry on Staphylococcus aureus in fixation or arthroplasty showed higher rates of MRSA in North American patients and poorer subjective outcomes among those with MRSA vs. methicillin-sensitive S. aureus.