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Janus Kinase Inhibitor

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July 03, 2023
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VIDEO: Role of JAK inhibitors in RA treatment

VIDEO: Role of JAK inhibitors in RA treatment

In this video, John M. Davis, III, MD, clinical rheumatologist and professor of medicine at Mayo Clinic College of Medicine and Science, discusses the role of JAK inhibitors in rheumatoid arthritis treatment, and growing understanding of their effects.

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June 30, 2023
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Eosinophilic cellulitis may benefit from treatment targeting Janus kinase

Eosinophilic cellulitis may benefit from treatment targeting Janus kinase

Based on the pathogenesis of eosinophilic cellulitis, treatment targeting Janus kinase 1 and 2 should be developed to treat this disease, according to a study.

Clinical Guidance
Ankylosing Spondylitis
Assessment and Treatment

Janus Kinase (JAK) Inhibitors

Muhammad Asim Kahn, MD, FRCP, MACP; Nurullah Akkoç, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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June 26, 2023
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Litfulo becomes first FDA-approved treatment for adolescents with severe alopecia

Litfulo becomes first FDA-approved treatment for adolescents with severe alopecia

The FDA has approved Litfulo, a once-daily oral treatment, for the treatment of severe alopecia in individuals aged 12 years and older, Pfizer announced in a press release.

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May 17, 2023
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More JAK inhibitors ‘coming down the pike’ despite poor understanding of mechanism

More JAK inhibitors ‘coming down the pike’ despite poor understanding of mechanism

The pipeline of Janus kinase inhibitors is robust even as researchers struggle to fully understand how they work, according to a presenter at the 2023 Biologic Therapies Summit.

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May 02, 2023
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VIDEO: Reduce JAK inhibitors 'cautiously and slowly' in patients with alopecia areata

VIDEO: Reduce JAK inhibitors 'cautiously and slowly' in patients with alopecia areata

NEW ORLEANS — In this Healio video exclusive, Ronda S. Farah, MD, discusses how reducing Janus kinase inhibitor dosages in patients with alopecia areata should be completed safely.

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April 10, 2023
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‘No evidence’ of increased short-term cancer risk for JAK inhibitors vs. TNF inhibitors

‘No evidence’ of increased short-term cancer risk for JAK inhibitors vs. TNF inhibitors

Clinical data found “no evidence” of a higher short-term cancer risk, except for non-melanoma skin cancer, in patients with rheumatoid arthritis or psoriatic arthritis starting Janus kinase inhibitors vs. TNF inhibitors, researchers wrote.

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April 04, 2023
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VIDEO: 'Super exciting' results of second phase 3 deuruxolitinib trial

VIDEO: 'Super exciting' results of second phase 3 deuruxolitinib trial

NEW ORLEANS — In this Healio exclusive video, Brett King, MD, PhD, discusses highlights from the American Academy of Dermatology Annual Meeting, including results from the second phase 3 trial of deuruxolitinib.

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March 21, 2023
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Patients with lichen planus show improvement with baracitinib

Patients with lichen planus show improvement with baracitinib

NEW ORLEANS — A first-in-human study found patients with lichen planus treated with the Janus kinase inhibitor baracitinib achieved almost total improvement, according to a presenter at the American Academy of Dermatology Annual Meeting.

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