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Isotretinoin

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December 12, 2023
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Isotretinoin not associated with increased risk for suicide, psychiatric conditions

Isotretinoin is not associated with an increased risk for suicide or psychiatric conditions on a population level, according to a study.

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December 11, 2023
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FDA issues required iPledge REMS modifications to isotretinoin manufacturers

The FDA has issued a notification to isotretinoin manufacturers to modify the iPledge Risk Evaluation and Mitigation Strategy to minimize procedural burdens on prescribers, pharmacists and patients.

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November 16, 2023
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Healio Minute Podcast, Dermatology Edition: Top Headlines - Week of November 13, 2023

In this edition, dermatologists ‘uniquely positioned’ to aid human trafficking victims; FDA approves Cosentyx for hidradenitis suppurativa and more.

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November 07, 2023
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Isotretinoin efficacious in seborrheic dermatitis treatment

CHICAGO — Isotretinoin can be a helpful addition to the toolbox for seborrheic dermatitis treatment, according to a study presented at the American Society for Dermatologic Surgery Annual Meeting.

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August 16, 2023
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M-PDT efficacy similar to isotretinoin in acne vulgaris

Modified 5-aminolevulinic acid photodynamic therapy was as effective as isotretinoin in the treatment of severe acne with a faster onset, according to a small study.

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June 21, 2023
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TMB-001 safety results show minimal systemic absorption of isotretinoin

In new pharmacokinetic analyses, patients treated with TMB-001 0.05% ointment for congenital ichthyosis experienced minimal systemic absorption of isotretinoin or its major metabolites, Timber Pharmaceuticals announced in a press release.

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May 12, 2023
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Changes in mood during isotretinoin treatment for acne vulgaris ‘may be multifactorial’

While some adolescents treated with isotretinoin for moderate to severe acne vulgaris reported mood-changes, a majority experienced improvement in symptoms and completed treatment, according to a study.

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April 14, 2023
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Topical isotretinoin ointment shows ‘reassuring’ efficacy, safety in congenital ichthyosis

Two formulations of a novel topical isotretinoin ointment formulation were associated with improvements over vehicle in patients with two types of congenital ichthyosis, according to a study.

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February 07, 2023
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IBD risk in acne may be due to ‘shared mechanistic pathways’

While acne was associated with incidence of inflammatory bowel disease, two drug classes used to treat acne had no such association, according to a study.

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January 25, 2023
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Fewer lab tests needed for pediatric patients on isotretinoin

WAILEA, Hawaii — For pediatric acne patients on isotretinoin, laboratory monitoring is still necessary, but not at the levels previously believed, according to a presentation at the Maui Derm meeting.

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