Isotretinoin

The risk for acne relapse following isotretinoin use is reduced with higher cumulative doses, suggesting individualized treatment plans based on patients’ goals could maximize efficacy, according to researchers.

It has been 9 months since the FDA released recommended changes to the iPledge Risk Evaluation and Mitigation Strategy, and providers are growing increasingly frustrated at a perceived lack of transparency and implementation plan.

Once-daily micronized isotretinoin can be administered without food for the treatment of patients with severe acne vulgaris, allowing for the potential increase of patient adherence, according to a study.

Isotretinoin is generally effective and well tolerated for acne treatment in patients receiving masculinizing gender-affirming care, but barriers can impede treatment success, according to a study.

Healio has compiled May’s most-read news in dermatology.

Isotretinoin is associated with a clinically marginal increased risk for severe adverse events, leading researchers to advise routine blood testing commence shortly after initiation, according to a study.

Beneath the Surface is a video series in which Joel M. Gelfand, MD, MSCE, Healio Dermatology Chief Medical Editor, discusses hot topics in the field with leading experts.

A large proportion of adolescent patients treated with isotretinoin for acne had a history of a psychiatric diagnosis, but most were not diagnosed with additional psychiatric diagnoses or symptoms during treatment, according to a study.

The American Academy of Dermatology has released new care guidelines for acne vulgaris, according to a press release.

In this edition, an advocacy group petitions the FDA for stronger safety warnings for Botox, melanoma regression is associated with improved prognosis and more.