Iron

Iron deficiency may be linked to non-dialysis-dependent chronic kidney disease and mortality in patients without anemia, according to results of a nationwide cohort study.

Iron deficiency during pregnancy went underrecognized and undertreated among a large sample of unique deliveries at Mayo Clinic, according to study results presented at ASH Annual Meeting and Exposition.

Canagliflozin was associated with increased iron utilization and improved hemoglobin levels for adults with type 2 diabetes and chronic kidney disease, according to data published in Nephrology Dialysis Transplantation.

In a final recommendation statement, the U.S. Preventative Services Task Force said there is insufficient evidence to recommend for or against the use of iron supplements during pregnancy.

More than half of people with iron deficiency continued to have low iron levels 3 years after diagnosis, according to retrospective study results.

When group 2 innate lymphoid cells become overactive, they can cause excessive inflammation and tighten the airways. But these immune cells depend on iron to generate energy.

While clinical trials have shown hypoxia-inducible factor prolyl hydroxylase inhibitors to be non-inferior to other anemia drugs, questions remain about IV or oral iron supplementation and inflammation, according to a new report.

In adults with HF with reduced ejection fraction and iron deficiency, ferric carboxymaltose modestly improved the endpoint of death, HF hospitalization and 6-minute walk distance but did not achieve the prespecified significance level.

Intravenous iron therapy did not improve exercise capacity in nonanemic patients with iron deficiency who have chronic kidney disease, according to recently published data.

Adults with HF after hospitalization for STEMI have lower serum iron levels compared with those without HF after STEMI, data from a retrospective case-control study show.