Intravenous Immunoglobulin

Glucocorticoids alone demonstrate similar recovery rates as intravenous immunoglobin, or combination therapy with both, in patients with multisystem inflammatory syndrome in children, according to data published in The Lancet Rheumatology.

In a case study of three patients with COVID-19 vaccine-induced immune thrombotic thrombocytopenia, starting intravenous immune globulin was linked to reduced antibody-induced platelet activation in serum, according to data.

In a cohort of four children and four adults with multisystem inflammatory syndrome, children generally had superior outcomes after discharge, noted a speaker at the 2021 North American Young Rheumatology Investigator Forum.

There is no evidence that recovery from multisystem inflammatory syndrome in children differs following treatment with glucocorticoids alone, intravenous immune globulin alone or a combination of the two, according to data.

Intravenous immunoglobulin 10% in doses of 2 g/kg demonstrated significantly higher treatment response rates, compared with placebo, in patients with dermatomyositis, according to a speaker at the EULAR 2021 Congress.

There have been nearly 1,100 measles cases in the United States in the first half of 2019 — more cases of measles than in any year since the disease was declared eliminated in the U.S. in 2000. As of July 25, 30 states have reported cases of measles, with outbreaks currently ongoing in five jurisdictions across the country.

In this installment of In Practice, Frederick L. Locke, MD, Co-Leader of the Immunology Program and Director of the Immune Cell Therapy Program at Moffitt Cancer Center, discusses the side effects and toxicities of CAR T-cell treatments. Though he acknowledges they are common, he emphasizes that they should not hinder the referral of patients who are candidates for these potentially ‘lifesaving treatments.’