Intraocular Inflammation

A 30-year-old man presented to the New England Eye Center for decreased vision with a central black spot in his vision for 1 week. He denied flashes, floaters, pain and headache.

The American Academy of Ophthalmology IRIS Registry is a centralized data repository that leverages the expanded use of electronic health records to collect real-world data that can be used to improve patient care and outcomes.

A 56-year-old woman presented to the ophthalmology office at the Lahey Clinic with 1 week of left eye pain associated with burning, injection and a left-sided headache without any vision changes.

Contact lens sensors that recorded ocular dimensional changes among patients with primary open-angle glaucoma are useful to identify risk for progression, according to research published in the Journal of Glaucoma.

Patients with glaucoma had significantly higher ocular redness than patients without glaucoma, according to a study published in the European Journal of Ophthalmology.

While further analysis of trial data confirms efficacy and safety events in real-world practice continue to be monitored, the attitude of retina specialists toward the newest FDA-approved anti-VEGF agent remains open but cautious.

Ongoing investigations of real-world data show patients with prior intraocular inflammation may be at higher risk for retinal vasculitis and/or retinal vascular occlusion after brolucizumab injections, according to a speaker.

A dominant topic for the ASRS Research and Safety in Therapeutics committee has been brolucizumab-related issues, particularly the risk for occlusive vasculitis and vision loss following treatment for neovascular AMD.

The FDA approved a label update for Beovu to include safety information about retinal vasculitis and retinal vascular occlusion, according to a Novartis press release.

Novartis is conducting a comprehensive product quality review of Beovu, a treatment for wet age-related macular degeneration, after the American Society of Retina Specialists shared an update with its membership on possible side effects of the therapy.