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Intrahepatic Cholestasis

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March 14, 2024
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FDA approves Livmarli for pruritus in progressive familial intrahepatic cholestasis

FDA approves Livmarli for pruritus in progressive familial intrahepatic cholestasis

The FDA has approved Mirum Pharmaceuticals’ Livmarli oral solution for treatment of cholestatic pruritus in patients aged 5 years and older with progressive familial intrahepatic cholestasis, according to a company release.

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August 03, 2023
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Early delivery, low stillbirth rate seen with pregnancy-related liver disorder

Early delivery, low stillbirth rate seen with pregnancy-related liver disorder

Women with intrahepatic cholestasis of pregnancy delivered earlier and had a lower percentage of stillbirths compared with women without the liver disorder, researchers reported in the American Journal of Obstetrics & Gynecology.

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November 08, 2022
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VIDEO: Livmarli reduces pruritus in progressive familial intrahepatic cholestasis subtypes

VIDEO: Livmarli reduces pruritus in progressive familial intrahepatic cholestasis subtypes

WASHINGTON — In a Healio video exclusive, Alexander G. Miethke, MD, noted that Livmarli demonstrated significant reductions in pruritus and serum bile acids across multiple subtypes of progressive familial intrahepatic cholestasis.

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February 16, 2022
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New study details burden for caregivers of children with rare liver disease

New study details burden for caregivers of children with rare liver disease

Albireo Pharma Inc. announced the publication of the PICTURE study, which assessed the impact that progressive familial intrahepatic cholestasis has on caregivers, according to a company press release.

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November 15, 2021
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Odevixibat reduces markers of progressive familial intrahepatic cholestasis in children

Odevixibat treatment reduced levels of peripheral blood autotaxin, pruritus and serum bile acid among pediatric patients with progressive familial intrahepatic cholestasis, according to pooled data.

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July 21, 2021
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FDA approves Bylvay for treating progressive familial intrahepatic cholestasis

Albiero Pharma Inc. announced it received FDA approval for Bylvay to treat pruritus in all subtypes of progressive familial intrahepatic cholestasis.

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June 24, 2021
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VIDEO: Progressive familial intrahepatic cholestasis improves with use of novel agent

VIDEO: Progressive familial intrahepatic cholestasis improves with use of novel agent

In a video exclusive, Lorenzo D’Antiga, MD, Pappa Giovanni XXIII Hospital, said Bylvay induced a sustained improvement in cholestasis-related parameters in patients with progressive familial intrahepatic cholestasis.

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November 17, 2020
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VIDEO: Odevixibat well tolerated in progressive familial intrahepatic cholestasis

VIDEO: Odevixibat well tolerated in progressive familial intrahepatic cholestasis

In this exclusive video, Richard Thompson, MD, PhD, discussed results from two abstracts presented at The Liver Meeting Digital Experience on using odevixibat in progressive familial intrahepatic cholestasis.