Interstitial Lung Disease

Patients with severe interstitial lung disease who received heated and humidified nasal high-flow oxygen therapy had significant improvements in endurance, physiologic parameters and sensations during exercise.

Early intervention is critical for patients who are likely to progress to serious complications from systemic sclerosis-associated interstitial lung disease, according to a presenter at the Biologic Therapies Summit.

In a post hoc analysis of the INCREASE study, patients with interstitial lung disease-associated pulmonary hypertension who continued inhaled treprostinil were less likely to experience further disease progression events vs. placebo.

In the SENSCIS-ON trial, two-thirds of patients with systemic sclerosis-associated interstitial lung disease who continued nintedanib after completion of the SENSCIS trial maintained stable lung function or had improvement in lung function.

For physicians, pulmonary artery hypertension poses many challenges, including the need for greater awareness and better therapies, according to an expert who spoke with Healio.

Patients with idiopathic pulmonary fibrosis appear to have higher cumulative incidences of exertional and resting hypoxemia compared with patients with non-IPF fibrotic interstitial lung disease, researchers reported in Chest.

The Healio Editors have compiled a list of recent articles about pulmonary hypertension in recognition of World Pulmonary Hypertension Day.

The classically defined diffuse subtype of juvenile systemic sclerosis demonstrates more globally severe disease and higher interstitial lung disease frequency, whereas the limited cutaneous subtype has more frequent cardiac symptoms, data shows.

Combined rheumatoid factor and anti-citrullinated protein antibody seropositivity was strongly associated with prevalent rheumatoid arthritis-associated interstitial lung disease in a cohort of U.S. veterans, researchers reported.

A number of new therapies, including immunosuppressive drugs and drug combinations, have shown efficacy in mitigating scleroderma-associated interstitial lung disease, according to a speaker at the ACR State-of-the-Art Clinical Symposium.