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Interstitial Lung Disease

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February 28, 2025
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Admilparant slows lung function decline in IPF, progressive PF

Admilparant slows lung function decline in IPF, progressive PF

Receiving admilparant, an oral lysophosphatidic acid receptor 1 antagonist, for 26 weeks lowered percent-predicted FVC decline in idiopathic and progressive pulmonary fibrosis, according to study results.

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February 13, 2025
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Positive topline data reported in phase 3 trial of nerandomilast in progressive PF

Positive topline data reported in phase 3 trial of nerandomilast in progressive PF

Adults with progressive pulmonary fibrosis met the primary endpoint of absolute change in FVC with 52-week oral nerandomilast, an investigational phosphodiesterase 4B inhibitor, vs. placebo, according to FIBRONEER-ILD topline results.

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February 04, 2025
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TNF inhibitors do not increase adverse event risk in rheumatoid arthritis-associated ILD

TNF inhibitors do not increase adverse event risk in rheumatoid arthritis-associated ILD

Treatment with TNF inhibitors yielded no differences in outcomes vs. other antirheumatic therapies among U.S. veterans with rheumatoid arthritis-associated interstitial lung disease, according to data published in The Lancet Rheumatology.

News
January 30, 2025
4 min read
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Q&A: Online resource aids patients newly diagnosed with pulmonary fibrosis

Q&A: Online resource aids patients newly diagnosed with pulmonary fibrosis

Receiving a diagnosis for any disease/condition is not an easy experience. One organization hopes to make patients newly diagnosed with pulmonary fibrosis feel supported during this time via a new online educational resource.

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January 07, 2025
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Long-term elevated inflammation raises ILD risk in rheumatoid arthritis

Long-term elevated inflammation raises ILD risk in rheumatoid arthritis

Patients with rheumatoid arthritis who demonstrate consistent long-term elevation of inflammatory markers have an increased risk for interstitial lung disease, according to data published in Arthritis Research & Therapy.

News
December 17, 2024
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Deupirfenidone reduces FVC decline, well tolerated in IPF at 26 weeks

Deupirfenidone reduces FVC decline, well tolerated in IPF at 26 weeks

Patients with idiopathic pulmonary fibrosis had less FVC decline between baseline and 26 weeks with receipt of three daily doses of 825 mg deupirfenidone, according to phase 2b ELEVATE IPF trial results.

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December 12, 2024
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Mortality similar after single- vs double-lung transplant in autoimmune disease with ILD

Mortality similar after single- vs double-lung transplant in autoimmune disease with ILD

WASHINGTON — Patients with systemic autoimmune rheumatic disease who develop interstitial lung disease demonstrate similar 1-year mortality risks following either single- or double-lung transplant, according to data.

News
December 06, 2024
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New EULAR systemic sclerosis recommendations illuminate a ‘significantly changed’ field

New EULAR systemic sclerosis recommendations illuminate a ‘significantly changed’ field

EULAR has released new recommendations on the treatment of systemic sclerosis, advancing new treatments and updated approaches to key manifestations such as skin and lung fibrosis.

News
December 03, 2024
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VIDEO: Screening may become an option in the future for ILD in rheumatoid arthritis

VIDEO: Screening may become an option in the future for ILD in rheumatoid arthritis

WASHINGTON — Healio spoke with Jeffrey A. Sparks, MD, MMSc, about baseline results from the SAIL-RA study, which assesses which patients with rheumatoid arthritis may be at risk for developing interstitial lung disease.

News
November 21, 2024
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‘Promoting honest and accurate conversations’ key before pregnancy in patients with ILD

‘Promoting honest and accurate conversations’ key before pregnancy in patients with ILD

BOSTON — To help patients with interstitial lung disease lower the chances of having a sick baby, physicians must have “honest and accurate conversations” with them before pregnancy, according to a presentation at the CHEST Annual Meeting.

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