Interleukin-6
Interleukin-1 beta inhibition improves hemoglobin levels, reduces anemia incidence
Inflammation inhibition through the interleukin-1 beta/interleukin-6 signaling pathway reduced incidence of anemia and improved hemoglobin levels among patients with anemia, according to results of an exploratory analysis of randomized trial data published in Annals of Internal Medicine.
RISK RA: Certain ACPA antibodies, tenosynovitis predicted RA onset
ATLANTA — The presence of tenosynovitis, along with an anti-filaggrin peptide, were associated with the development of rheumatoid arthritis in a cohort of participants who underwent anti-citrullinated protein antibody testing, according to a speaker at ACR/ARP 2019.
Methotrexate inhibits progressive joint damage in hand OA, fails to improve pain, function
ATLANTA — Methotrexate significantly reduced the progression of joint damage among patients with erosive hand osteoarthritis, but demonstrated no significant improvement in pain or function over placebo, according to a presentation at the 2019 ACR/ARP Annual Meeting.