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Interleukin-17

Clinical Guidance
Psoriatic Arthritis
Overview

Genetics and Pathogenesis of Psoriatic Arthritis

Eric M. Ruderman, MD; Kenneth B. Gordon, MD

This is a description of an article from Clinical Guidance. This article is about genetics and psoriatic arthitis.

Clinical Guidance
Psoriasis
Overview

Genetics and Pathogenesis of Psoriasis

Eric M. Ruderman, MD; Kenneth B. Gordon, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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May 24, 2024
4 min read
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IL-17 inhibitors may break TNFi ‘glass ceiling’ in psoriatic arthritis prescribing

IL-17 inhibitors may break TNFi ‘glass ceiling’ in psoriatic arthritis prescribing

Although TNF inhibitors remain the first choice biologic for many rheumatologists treating psoriatic arthritis, interleukin-17 inhibitors may soon overtake them, according to a market analysis from Spherix Global Insights.

News
March 11, 2024
1 min read
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Izokibep meets ACR50 endpoint in PsA, has ‘deepening’ benefit in hidradenitis suppurativa

Izokibep meets ACR50 endpoint in PsA, has ‘deepening’ benefit in hidradenitis suppurativa

Izokibep achieved the primary endpoint of ACR50 response in a phase 2b/3 psoriatic arthritis trial, and demonstrated sustained, “deepening” benefit in hidradenitis suppurativa, according to top-line data from its manufacturer.

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February 22, 2024
2 min read
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New mechanisms, nanobody ‘revolution’ promising for psoriatic arthritis treatment

New mechanisms, nanobody ‘revolution’ promising for psoriatic arthritis treatment

SCOTTSDALE, Ariz. — Interleukin-17 targeting, a tyrosine kinase 2 inhibitor and the “nanobody revolution” represent a promising new frontier for psoriatic arthritis, according to a speaker here.

News
February 01, 2024
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VIDEO: Recent clinical trial results, ongoing research in polymyalgia rheumatica

VIDEO: Recent clinical trial results, ongoing research in polymyalgia rheumatica

In this video, Sebastian E. Sattui, MD, MS, discusses exciting research on polymyalgia rheumatica.

News
January 04, 2024
2 min read
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Two inflammatory markers independently predict heart disease risk

Two inflammatory markers independently predict heart disease risk

Among adults presenting with chest pain, those with CAD confirmed by angiography had significantly lower levels of the cytokines interleukin-4 and interleukin-17 compared with those without CAD, data show.

News
December 18, 2023
2 min read
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Sarilumab superior to placebo for achieving sustained remission in polymyalgia rheumatica

Sarilumab superior to placebo for achieving sustained remission in polymyalgia rheumatica

Among patients with polymyalgia rheumatica who relapse during glucocorticoid tapering, sarilumab is effective at enabling them achieve sustained remission and lowering cumulative glucocorticoid use, according to data.

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November 15, 2023
3 min read
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Women less likely than men to respond to advanced therapies in psoriatic arthritis

Women less likely than men to respond to advanced therapies in psoriatic arthritis

SAN DIEGO — In patients with psoriatic arthritis, those with female sex are less likely than those with male sex to achieve outcomes in randomized clinical trials for advanced therapies, according to data presented at ACR Convergence 2023.

News
August 02, 2023
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VIDEO: ‘Rethink your diagnosis’ if psoriasis does not clear after starting interleukins

VIDEO: ‘Rethink your diagnosis’ if psoriasis does not clear after starting interleukins

In this Healio video exclusive, Melodie Young, MSN, RN, ANP-C, discusses highlights in psoriasis from Maui Derm NP+PA.

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