Interferon

Most pediatric patients with Sjögren’s disease displayed an interferon signature in their blood and parotid gland tissue, which could help confirm diagnoses and shorten treatment delays, according to data presented at EULAR 2024 Congress.

For those with relapsing-remitting MS, treatment with diroximel fumarate was linked to better outcomes at 96 weeks compared with those given interferon beta-1a, according to a presentation at ECTRIMS 2023.

Researchers will study connections between eosinophilic esophagitis and interferon signaling, possibly paving the way for new treatments, with funding from the AAAAI Foundation’s 2023 Faculty Development awards.

SCOTTSDALE, Ariz. — Several new drugs and promising therapies, including chimeric antigen receptor T-cell therapy, have ushered in a “lupus renaissance,” said a speaker at the Basic and Clinical Immunology for the Busy Clinician symposium.

A single dose of pegylated interferon lambda used as early treatment in patients with COVID-19 was effective in lowering the total occurrences of hospitalization and ED visits, a study published in The New England Journal of Medicine found.

The addition of interferon alfa to temozolomide significantly extended survival among patients with newly diagnosed high-grade gliomas, according to data published in JAMA Network Open.

WASHINGTON — Pegylated interferon alpha potentiated the antiviral activity of VIR-2218 in a small subset of noncirrhotic patients with chronic hepatitis B, according to preliminary data presented at The Liver Meeting.

SAN FRANCISCO — Treatment with inhaled interferon beta failed to improve discharge and recovery in patients hospitalized with moderate COVID-19, according to results of the phase 3 SPRINTER trial.

Iberdomide, a novel oral cereblon modulator, was superior to a placebo only in patients with systemic lupus erythematosus who received the highest dose in a phase 2 trial, albeit with a high incidence of adverse events, according to data.