Insulin

Algorithms for initiating insulin among noncritically ill adults varied widely across 20 U.S. academic hospitals, according to a brief report published in Diabetes Technology & Therapeutics.

Changing in-hospital nutritional insulin administration from before meals to after meals lowered hypoglycemia rates at a community hospital, according to study findings published in Diabetes Research and Clinical Practice.

Researchers found that adults with overweight or obesity lost more weight with tirzepatide than semaglutide in a head-to-head comparison of the medications using electronic medical records data.

The FDA declined to approve once-weekly basal insulin icodec for the treatment of diabetes and is requesting more information from Novo Nordisk, according to a company press release.

People with type 2 diabetes who use a GLP-1 receptor agonist have a lower risk for 10 types of obesity-associated cancer compared with those who use insulin, according to data published in JAMA Network Open.

ORLANDO — Adults with type 1 diabetes had larger reductions in HbA1c using a mobile app that made recommended adjustments to insulin therapy than users who did not receive weekly adjustments, according to a speaker.

BOSTON — Tumor samples from Black women diagnosed with triple-negative breast cancer expressed higher levels of insulin signaling than samples from white women, suggesting hyperinsulinemia may play a role in disease outcomes, data show.

An FDA committee declined to recommend approval for a once-weekly insulin to improve glycemic control for adults with type 1 diabetes.

Women with obesity who undergo bariatric surgery and have higher levels of insulin have a lower risk for breast cancer than women who do not undergo surgery, according to findings published in JAMA Surgery.