Insulin Resistance

LAS VEGAS — Adults with type 2 diabetes can experience multiple diabetes-specific benefits beyond weight loss by undertaking a low-carbohydrate diet, although potential risks must be addressed, according to a speaker at ObesityWeek.

LAS VEGAS— The epidemics of obesity and type 2 diabetes continue to grow, and several challenging questions may hold the clues to targeting the mechanisms behind the two chronic conditions, according to a presenter at ObesityWeek.

Researchers determined that higher liver fat content independent of BMI correlated with an adverse cardio-metabolic risk profile among children.

Researchers found that while consumption of red and processed meat, poultry, and cholesterol correlated with nonalcoholic fatty liver disease, dietary fiber intake may reduce the risk for fatty liver and related advanced liver disease, according to data from a multiethnic cohort study.

Results from the EVIDENCES IV trial showed that saroglitazar magnesium achieved its primary endpoint of reduced alanine aminotransferase in patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, according to a press release from Zydus Calida.

High serum sclerostin levels are independently correlated with low muscle mass in healthy Korean adults, according to findings published in Bone.

Combined, diabetes, obesity and insulin resistance are the most common cause of preventable death in the United States, responsible for millions of deaths and more than $600 billion in health care costs. The Cardiometabolic Health Congress, the largest U.S.-based multidisciplinary conference centered on the management and prevention of CV and metabolic disease, is being held October 10 to 13 in Chicago for health care practitioners committed to joining the fight against cardiometabolic disease.

Prevalence of nonalcoholic fatty liver disease — and its more severe stage, nonalcoholic steatohepatitis, or NASH, in particular — is increasing in developed countries. The condition has surpassed alcoholism as a cause of cirrhosis and will soon be the primary cause of liver transplantation in the United States, exceeding hepatitis C, according to Kenneth Cusi, MD, FACP, FACE, chief of the division of endocrinology, diabetes and metabolism at University of Florida.

In a cohort of adults assessed for sleep issues, those in the highest quartile of apolipoprotein B to apolipoprotein A-I ratio were at the greatest risk for obstructive sleep apnea and insulin resistance, according to findings published in Nutrition, Metabolism & Cardiovascular Diseases.

Risk for developing type 2 diabetes is not modified by consuming more omega-3, omega-6 and/or total polyunsaturated fatty acids, according to findings published in BMJ.