Inflammatory Disease

Atherosclerotic CVD has long been recognized as an inflammatory disease.

Patients with psoriatic arthritis have much to be hopeful about, with understanding of the disease increasing and an expanded range of treatment options available, according to a presenter at the 2020 Rheumatology Nurses Society Annual Conference.

Cellular senescence has both positive and negative effects in the body.

Investigators have identified inflammatory proteins, known as neutrophil extracellular traps, that may contribute to the onset of cardiac complications among patients with COVID-19 infection, according to study results published in Blood.

Adults with inflammatory disease prescribed glucocorticoid therapy experienced an improvement in several metabolic parameters after adding metformin therapy for 12 weeks compared with similar adults assigned placebo, according to findings from a phase 2 study published in The Lancet Diabetes & Endocrinology.

Immune-mediated inflammatory diseases (IMIDs) are a group of clinically heterogeneous disorders, including rheumatoid arthritis, psoriasis, psoriatic arthritis, giant cell arteritis, systemic lupus erythematosus, and axial spondyloarthritis, that share a similar immunopathology. Recognizing the underlying immunopathological mechanisms of these disorders is essential for understanding how current and emerging therapies exert their effects. In this CME activity, recorded during the Association of Women in Rheumatology National Conference, experts in the field examine common signaling pathways in IMIDs, evaluate recent clinical evidence for available and emerging immune-based therapies that target these pathways, assess the utilization of biomarkers for the identification of patients with early inflammatory disease, and evaluate the mechanisms of cancer immunotherapies as they relate to both an antitumor response and the potential for autoimmunity.