Inflammation

Adults with moderate to severe COPD and type 2 inflammation receiving dupilumab vs. placebo had fewer exacerbations and improved lung function at 52 weeks, according to topline results from the phase 3 NOTUS trial.

Medtronic announced the U.S. launch of its left atrial appendage exclusion system for use during cardiac surgery in patients with preoperative atrial fibrillation.

The efficacy of orismilast is greater than placebo in patients with moderate to severe psoriasis, according to phase 2b trial results.

PHILADELPHIA — In the CLEAR Outcomes cohort of patients with statin intolerance, inflammation predicted risk for CV events and death more strongly than cholesterol, researchers reported at the American Heart Association Scientific Sessions.

PHILADELPHIA — Although rare, hypercalcemia should be treated as a potential threat for patients with from severe tophaceous gout, according to a case study presented at the ASN Kidney Week.

BOSTON — Treatment with TERN-501, a selective thyroid hormone receptor beta agonist, reduced liver fat content and fibro-inflammation among patients with presumed metabolic dysfunction-associated steatohepatitis, late-breaking data showed.

A multidisciplinary approach is key to treating patients with corneal nerve dysfunction and neuropathic ocular pain, according to a speaker at Twin Cities Ocular Surface Disease Symposium.

PHILADELPHIA — Compared with controls, patients with chronic kidney disease showed greater accumulation of intermuscular adipose tissue that has a strong association with insulin resistance, according to data presented at ASN Kidney Week.

PHILADELPHIA — In this Healio exclusive, Deepak L. Bhatt, MD, MPH, provides his perspective on research presented at the American Heart Association Scientific Sessions.

A Canadian neuroimaging company has received an investment from the Alzheimer’s Drug Discovery Foundation to accelerate development of novel biomarkers for Alzheimer’s disease and related dementias.