Incidence

A patient diagnosed with psoriatic arthritis at 18 to 40 years of age carries a greater risk for joint surgery than someone aged 60 years or older in the general population, according to findings published in Annals of the Rheumatic Diseases.

Older Japanese adults with type 2 diabetes prescribed to the SGLT2 inhibitor ipragliflozin experienced a decline in HbA1c and body weight over 12 months that was similar to adults younger than 65 years, although researchers observed more serious adverse drug reactions among the older population, according to findings published in Current Medical Research and Opinion.

The top stories in hematology/oncology last week both resulted from FDA actions: Allergan’s agreeing to the agency’s request to recall specific models of its breast implants that may be related to a rare type of lymphoma and the agency granting breakthrough therapy designation to the Keytruda-Lenvima combination for hepatocellular carcinoma.

SAN ANTONIO — There continues to be an unmet need regarding CVD prevention in patients who are currently receiving cancer treatment or are cancer survivors, although partnership with cardiology and oncology may help improve outcomes, according to a presentation at the American Society for Preventive Cardiology Congress on CVD Prevention.

Colorectal cancer diagnoses among individuals aged younger than 50 years continued to increase in the United States over the past decade, according to results of a retrospective study published in Cancer.

Placing an inferior vena cava filter in patients within 72 hours of major trauma did not reduce incidence of symptomatic pulmonary embolism or death at 90 days, according to results of a randomized prospective trial published in The New England Journal of Medicine.

SAN FRANCISCO — A head-to-head comparison of the sulfonylurea glimepiride against the DPP-IV inhibitor linagliptin in a cohort of more than 6,000 adults with type 2 diabetes demonstrated no between-group differences for incidence of nonfatal myocardial infarction, nonfatal stroke and cardiovascular death during a median of 6 years, according to data from the CAROLINA trial presented at the American Diabetes Association Scientific Sessions.

Venous thromboembolism — which includes deep vein thrombosis and pulmonary embolism — causes up to 100,000 deaths annually in the United States and affects patients in numerous health care settings, regardless of age.

The overall incidence of meningococcal disease is low among college students in the United States, but they were over three times more likely to develop meningococcal B disease, or MenB, compared with those who did not attend college, according to research published in Pediatrics. The increased risk for disease among this population highlights the importance of vaccination, researchers said.

ICU patients colonized with Acinetobacter baumannii upon admission were more likely to develop subsequent positive clinical cultures for the bacterium and die during their hospital stay, according to findings from a retrospective cohort analysis.