Imperial College London
‘Amazing’ evidence shows lower Alzheimer’s disease risk among people with cancer
Older adults with cancer had a lower risk for Alzheimer’s disease and related dementias than cancer-free individuals of the same age, according to results of a longitudinal retrospective study.
DOACs lower stroke, raise hemorrhage risk in those with prior brain hemorrhage plus AF
The benefit of direct oral anticoagulants on stroke risk in patients with prior intracerebral hemorrhage and atrial fibrillation was partially offset by increased risk for future hemorrhage risk, a speaker reported.
Blood cancer during pregnancy increases severe maternal morbidity 22-fold
Women diagnosed with a hematologic malignancy during pregnancy had a 22-fold higher rate of severe maternal morbidity than those who did not have blood cancer, according to study results.
Vutrisiran reduces death, CV events in ATTR amyloidosis with cardiomyopathy
Among patients with transthyretin amyloidosis with cardiomyopathy, vutrisiran, an RNA interference agent, reduced risk for death and recurrent CV events compared with placebo, according to the results of the HELIOS-B trial.
Early age at menarche linked to carotid intima-media thickness
Genetically predicted early age at menarche was associated with increased carotid intima-media thickness, an early marker of subclinical atherosclerosis and medial hypertrophy, researchers reported.
SELECT: Semaglutide provides CV benefits for adults with obesity, regardless of HbA1c
ORLANDO — Semaglutide reduces risk for cardiovascular events among adults with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or change in HbA1c, according to data from the SELECT trial.
Mental health, sexual function worsen for men in first year of quitting steroids
BOSTON — In the first year after stopping anabolic steroid misuse, men had worse sexual function than those who continued using or never used the agents as well as more depression and anxiety, according to a presenter at ENDO 2024.
Short-term testosterone therapy improves quality of life, sexual function for men
Testosterone therapy improves sexual function and quality of life for men with a baseline serum testosterone of less than 12 nmol/L, though less improvement was observed for older men and those with obesity, data show.
High heterogeneity observed for baseline variables included in pituitary adenoma studies
Common data elements are needed to reduce heterogeneity in studies on transsphenoidal pituitary adenoma surgery, according to a systematic review published in Pituitary.
High blood pressure, cholesterol before age 55 tied to elevated heart disease risk
Researchers reported that exposure to elevated LDL and elevated systolic BP before age 55 years is associated with increased coronary heart disease risk independent of later-life BP and cholesterol levels.