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Immunotherapy

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April 01, 2021
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FDA clears IND application for immunotherapy combination to treat solid tumors

FDA clears IND application for immunotherapy combination to treat solid tumors

The FDA cleared an investigational new drug application for the combination of AFM24 and SNK-01 in patients with solid tumors that express epidermal growth factor receptor, according to a joint press release from each agent’s manufacturer.

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March 31, 2021
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VIDEO: Immunotherapy has 'come of age' in breast cancer

VIDEO: Immunotherapy has 'come of age' in breast cancer

In this video, Debu Tripathy, MD, professor and chair of the department of breast medical oncology at The University of Texas MD Anderson Cancer Center and a HemOnc Today Editorial Board member, discussed immunotherapy updates presented at the 38th Annual Miami Breast Cancer Conference.

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March 25, 2021
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Chronic adverse events more common than thought after adjuvant immunotherapy for melanoma

Chronic adverse events more common than thought after adjuvant immunotherapy for melanoma

Chronic immune-related adverse events appeared more common than previously thought among patients with stage III to stage IV melanoma who received adjuvant anti-PD-1 therapy, according to study results published in JAMA Oncology.

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March 25, 2021
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Relatlimab-nivolumab combination extends PFS in metastatic melanoma

Relatlimab-nivolumab combination extends PFS in metastatic melanoma

A trial designed to evaluate the addition of relatlimab to nivolumab for untreated metastatic or unresectable melanoma met its primary endpoint of improved PFS, according to topline data released by the agent’s manufacturer.

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March 22, 2021
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Chemotherapy for gynecologic cancer does not increase COVID-19 hospitalization, death

Chemotherapy for gynecologic cancer does not increase COVID-19 hospitalization, death

Chemotherapy did not increase risk for hospitalization or death due to COVID-19 among women with gynecologic cancer, according to results presented at the virtual Society of Gynecologic Oncology Annual Meeting on Women’s Cancer.

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March 22, 2021
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Managing lung cancer, COVID-19: Balancing quality treatment with risk mitigation

Managing lung cancer, COVID-19: Balancing quality treatment with risk mitigation

The COVID-19 pandemic presents many challenges to health care and, more specifically, cancer care. Patients with lung cancer have high rates of complication due to their underlying disease.

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March 20, 2021
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Neoadjuvant combination immunotherapy ‘promising’ for early-stage NSCLC

Neoadjuvant combination immunotherapy ‘promising’ for early-stage NSCLC

Neoadjuvant combination immunotherapy improved outcomes for patients with operable non-small cell lung cancer, according to results of the randomized phase 2 NEOSTAR trial.

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March 19, 2021
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VIDEO: Immunotherapy is the ‘big bang’ at MBCC

VIDEO: Immunotherapy is the ‘big bang’ at MBCC

In this video, Kelly K. Hunt, MD, FACS, FSSO, professor and chair of the department of breast surgical oncology at The University of Texas MD Anderson Cancer Center, highlighted updated presentations in immunotherapy at the virtual 38th Annual Miami Breast Cancer Conference.

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March 19, 2021
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FDA plans public meeting to reevaluate accelerated approvals of cancer drugs

FDA plans public meeting to reevaluate accelerated approvals of cancer drugs

FDA’s Oncologic Drugs Advisory Committee plans to hold a public meeting April 27-29 to review six indications for cancer drugs granted accelerated approval that subsequently failed to show clinical benefit in confirmatory trials.

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March 15, 2021
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Tumor mutational burden does not predict response to immunotherapy in all cancer types

Tumor mutational burden does not predict response to immunotherapy in all cancer types

Tumor mutational burden predicted immunotherapy response for some, but not all, cancer types, according to study results published in Annals of Oncology.

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