Immunotherapy
Top in allergy/asthma: Disinfectants affect asthma; rates of new peanut allergies are low
More frequent use of household cleaning products led to higher odds of current or uncontrolled asthma. The highest odds were associated with the use of disinfectant wipes, according to a recent study.
Top news of January: Dupilumab for eosinophilic esophagitis, cell phone allergy, more
Healio compiled the most-read news in allergy, asthma and immunology posted in January.
Uninsured U.S. cancer cases decline despite ‘alarming’ lack of coverage in some states
The proportion of individuals with newly diagnosed cancer who lacked insurance in the U.S. declined significantly from 2010 to 2019, according to data published in Health Affairs Scholar.
‘Groundbreaking’ injectable nivolumab reduces treatment burden for advanced kidney cancer
Subcutaneous nivolumab can reduce burdens on the health care system and patients with pretreated advanced or metastatic clear cell renal cell carcinoma compared with its IV formulation, according to data from a phase 3 CheckMate 67T trial.
Intralesional immunotherapy shows potential for treating various skin cancers
Intralesional immunotherapy shows potential as a treatment for cutaneous malignancies, including nonmelanoma skin cancer, according to a speaker at this year’s ODAC Dermatology, Aesthetic & Surgical Conference.
Plasma p-tau assay highly accurate in identifying Alzheimer’s-related pathology
A plasma phosphorylated-tau217 assay demonstrated a high degree of accuracy in identifying biomarkers consistent with Alzheimer’s disease-related pathology, according to research from JAMA Neurology.
Addition of immunotherapy to perioperative cancer treatment linked to more toxicity
The addition of immunotherapy to perioperative conventional cancer therapy appeared linked to more grade 3 to grade 4 treatment related adverse events, according to findings published in The Lancet Oncology.
‘Shocking’ results reveal imaging can detect early response to immunotherapy for melanoma
Metabolic changes can be identified in patients with advanced melanoma by imaging tumors within 1 week of beginning immunotherapy, according to a study published in Clinical Cancer Research.
FDA requires boxed safety warning for all CAR T-cell therapies
The FDA has requested manufacturers of commercially available chimeric antigen receptor T-cell therapies now include a boxed safety warning regarding the risk for secondary T-cell malignancies on prescribing labels.
Peanut immunotherapy uses synthetic peptides for safety, durability
An immunotherapy comprising seven synthetic peptides may provide a safe and durable alternative to immunotherapies based on whole peanuts, according to a study published in Allergy.