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Immune Checkpoint Inhibitor

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April 22, 2024
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Checkpoint inhibitor-related toxicities and patient advocacy: Who will stand up?

Checkpoint inhibitor-related toxicities and patient advocacy: Who will stand up?

I recently had the pleasure of attending a symposium at the Cleveland Clinic that featured an outstanding review of immune-related adverse events, and I was reminded of how far we have come in the decade since I first became involved in the evolution of this disease class.

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April 18, 2024
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New data ‘offer some hope’ that checkpoint inhibitors may be safe for pregnant women

New data ‘offer some hope’ that checkpoint inhibitors may be safe for pregnant women

Use of immune checkpoint inhibitors for pregnant women with cancer may be safer than previously thought, according to study results published in JAMA Network Open.

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April 14, 2024
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Relapse, disease progression uncommon with immune checkpoint inhibitors in MS

Relapse, disease progression uncommon with immune checkpoint inhibitors in MS

DENVER – For older adults with MS and signs of cancer, treatment with immune checkpoint inhibitors was safe and prevented relapse or disease progression, according to interim research.

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October 30, 2023
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Dostarlimab regimen extends survival for women with advanced endometrial cancer

Dostarlimab regimen extends survival for women with advanced endometrial cancer

A regimen containing dostarlimab plus standard-of-care chemotherapy significantly improved OS compared with chemotherapy alone in women with primary advanced or recurrent endometrial cancer, according to the agent’s manufacturer.

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October 15, 2023
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Immunotherapy specialist appointed research center's scientific director

Immunotherapy specialist appointed research center's scientific director

Fred Hutchinson Cancer Center appointed Lawrence Fong, MD, as scientific director of the Immunotherapy Integrated Research Center.

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October 09, 2023
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Anti-CTLA-4 immune checkpoint inhibitor may hold promise for glioblastoma treatment

Anti-CTLA-4 immune checkpoint inhibitor may hold promise for glioblastoma treatment

Researchers at Salk Institute for Biological Studies have achieved promising results in early studies using an anti-CTLA-4 antibody for treatment of glioblastoma, the most common and deadliest form of brain cancer.

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September 05, 2023
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Immunotherapy may benefit certain patients with penile cancer

Immunotherapy may benefit certain patients with penile cancer

Immune checkpoint inhibitors may confer benefit to certain patients with advanced penile squamous cell carcinoma, according to retrospective study results.

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July 06, 2023
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Radiotherapy fails to improve effectiveness of checkpoint inhibitors for solid tumors

Radiotherapy fails to improve effectiveness of checkpoint inhibitors for solid tumors

The addition of stereotactic body radiotherapy to immune checkpoint inhibitors failed to significantly extend survival among individuals with advanced solid tumors, results of the randomized phase 2 CHEERS trial showed.

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July 05, 2023
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Immune checkpoint inhibitors ‘safe and effective’ for people living with HIV, cancer

Immune checkpoint inhibitors ‘safe and effective’ for people living with HIV, cancer

People living with HIV and various cancer types may be safely treated with immune checkpoint inhibitors, according to results of a retrospective study published in Journal of Clinical Oncology.

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June 29, 2023
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Incidence of cancer-associated thrombosis remains high over time, varies with therapy

Incidence of cancer-associated thrombosis remains high over time, varies with therapy

Incidence of venous thromboembolism remained high among patients with cancer even as the treatment landscape has evolved over the past 16 years, according to data published in JAMA Network Open.

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