Idiopathic Pulmonary Fibrosis

In patients with idiopathic pulmonary fibrosis, pirfenidone delayed new-onset respiratory adverse events and antibiotic prescriptions, but did not delay new prescription of concomitant antitussive drugs compared with placebo.

Treatment with low-dose azithromycin for chronic cough in patients with idiopathic pulmonary fibrosis did not significantly improve cough-related quality of life, severity or frequency compared with placebo.

The addition of co-trimoxazole or doxycycline to usual care did not significantly improve time to respiratory hospitalization or death in adults with idiopathic pulmonary fibrosis, according to results of the CleanUP-IPF trial.

Patients with idiopathic pulmonary fibrosis living in areas with high neighborhood-level disadvantage may have worse survival and lower odds of lung transplantation, researchers reported.

Patients with idiopathic pulmonary fibrosis appear to have higher cumulative incidences of exertional and resting hypoxemia compared with patients with non-IPF fibrotic interstitial lung disease, researchers reported in Chest.

Active and passive tobacco smoking around birth was associated with an increase in the risk for idiopathic pulmonary fibrosis, researchers reported in Chest.

A review published in Chest highlights the need for a standardized method to identify and categorize patients’ environmental exposures to aid in the diagnosis and prevention of interstitial lung disease progression.

In a new study, the odds of having gastroesophageal reflux disease were nearly two times higher in patients with idiopathic pulmonary fibrosis compared with adults without idiopathic pulmonary fibrosis.

Use of proton pump inhibitors in patients with idiopathic pulmonary fibrosis was not associated with lower mortality or hospitalization incidence, according to results of a large, real-world study.

Age-adjusted mortality rates for idiopathic pulmonary fibrosis decreased from 2004 to 2017 in the United States, according to a new study published in CHEST.