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Idiopathic Pulmonary Fibrosis

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November 27, 2023
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ILD treatment differs by sex, race across countries

ILD treatment differs by sex, race across countries

The prevalence of patients with interstitial lung disease who receive treatment varied across countries, with some sex- and race-based differences, according to results published in CHEST.

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October 16, 2023
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Combination therapy with nintedanib plus pirfenidone appears well tolerated in IPF

Combination therapy with nintedanib plus pirfenidone appears well tolerated in IPF

HONOLULU — Treatment with nintedanib plus pirfenidone resulted in a similar frequency of adverse events as monotherapy among patients with idiopathic pulmonary fibrosis, according to a systemic review presented at the CHEST Annual Meeting.

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October 09, 2023
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Reduced nintedanib dose shows comparable efficacy to higher dose in IPF

Reduced nintedanib dose shows comparable efficacy to higher dose in IPF

HONOLULU — Risk for mortality and hospitalization did not differ between patients with idiopathic pulmonary fibrosis taking 100 mg or 150 mg nintedanib twice daily, according to a real-world analysis presented at the CHEST Annual Meeting.

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August 29, 2023
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FDA grants orphan drug designation to zelasudil for IPF

FDA grants orphan drug designation to zelasudil for IPF

The FDA granted orphan drug designation to zelasudil for treating patients with idiopathic pulmonary fibrosis, according to a press release from the drug’s manufacturer.

News
June 21, 2023
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Ziritaxestat fails to improve lung function in patients with idiopathic pulmonary fibrosis

Ziritaxestat fails to improve lung function in patients with idiopathic pulmonary fibrosis

WASHINGTON — In patients with idiopathic pulmonary fibrosis, yearly lung function decline rates did not improve with two different dosages of ziritaxestat, according to an American Thoracic Society International Conference presentation.

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February 28, 2023
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Raising pulmonary fibrosis awareness for Rare Disease Day

Raising pulmonary fibrosis awareness for Rare Disease Day

Almost 90% of Americans are unaware of the symptoms that signal pulmonary fibrosis due to the disease’s rarity, according to a Pulmonary Fibrosis Foundation survey.

News
February 09, 2023
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FDA grants orphan drug designation to AI-created drug for idiopathic pulmonary fibrosis

FDA grants orphan drug designation to AI-created drug for idiopathic pulmonary fibrosis

The FDA granted orphan drug designation to INS018_055, an anti-fibrotic small molecule inhibitor, for treating patients with idiopathic pulmonary fibrosis, according to a press release from the drug’s manufacturer.

News
December 29, 2022
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Deep learning may reduce need for lung biopsies in patients with ILD

Deep learning may reduce need for lung biopsies in patients with ILD

Compared with visual assessment, a deep learning model improved CT imaging prediction of histopathologic usual interstitial pneumonitis in patients with interstitial lung disease, according to study results published in CHEST.

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December 07, 2022
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FDA grants orphan drug designation to ifenprodil for IPF

FDA grants orphan drug designation to ifenprodil for IPF

The FDA granted orphan drug designation to ifenprodil for the treatment of patients with idiopathic pulmonary fibrosis, according to a press release from the drug’s manufacturer.

News
November 30, 2022
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Q&A: Investigational therapy shows potential for treating patients with IPF

Q&A: Investigational therapy shows potential for treating patients with IPF

Saracatinib appeared to be “equal or superior” in stopping fibrotic responses compared with two FDA-approved antifibrotic drugs, according to a preclinical study published in American Journal of Respiratory and Critical Care Medicine.

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