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Icahn School Of Medicine At Mount Sinai

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January 24, 2023
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Stereotactic body radiation extends survival in hepatocellular carcinoma

Stereotactic body radiation extends survival in hepatocellular carcinoma

Stereotactic body radiation therapy followed by sorafenib extended survival compared with sorafenib alone among patients with hepatocellular carcinoma, according to study results presented at ASCO Gastrointestinal Cancers Symposium.

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January 06, 2023
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EHR-based machine learning model yields novel marker for CAD risk, prognosis

EHR-based machine learning model yields novel marker for CAD risk, prognosis

An artificial intelligence-derived marker using electronic health records noninvasively quantified plaque burden and mortality risk for adults from two large biobank cohorts, offering an option for more targeted CAD diagnosis, data show.

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December 21, 2022
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Pelabresib-ruxolitinib combination reduces spleen volume, symptom score in myelofibrosis

Pelabresib-ruxolitinib combination reduces spleen volume, symptom score in myelofibrosis

Pelabresib plus ruxolitinib conferred benefit to Janus kinase inhibitor-naive patients with myelofibrosis, according to study results presented at ASH Annual Meeting and Exhibition.

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December 12, 2022
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Spaceflight may be linked to somatic mutations, increased risk for cancer, heart disease

Spaceflight may be linked to somatic mutations, increased risk for cancer, heart disease

Spaceflight may place astronauts at increased risk for developing mutations that can lead to cancer and heart disease, according to a study published in Nature Communications Biology.

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December 10, 2022
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Talquetamab shows ‘impressive’ efficacy for heavily pretreated advanced multiple myeloma

Talquetamab shows ‘impressive’ efficacy for heavily pretreated advanced multiple myeloma

NEW ORLEANS — Nearly three-quarters of patients who received talquetamab for relapsed or refractory multiple myeloma had an objective response to therapy, results of the phase 1/phase 2 MonumenTAL-1 trial showed.

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December 05, 2022
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ASCs linked with decreased health care utilization, expenditures for ACL reconstruction

ASCs linked with decreased health care utilization, expenditures for ACL reconstruction

Compared with outpatient hospitals, ASCs reduced total health care utilization and expenditures for ACL reconstruction in the United States from 2013 to 2017, according to published results.

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December 02, 2022
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Next-gen self-expanding valve improves alignment, implant depth in TAVR

Next-gen self-expanding valve improves alignment, implant depth in TAVR

In a real-world setting, a next-generation self-expanding transcatheter aortic valve replacement system showed improved commissural alignment and target implant depth compared with a prior system, researchers reported at PCR London Valves.

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November 18, 2022
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CAR-T destined for earlier lines of therapy in blood cancers, experts say

CAR-T destined for earlier lines of therapy in blood cancers, experts say

Despite data on the approach still being accumulated, a panel of experts at Chemotherapy Foundation Symposium predicted that chimeric antigen receptor T cells will become front-line therapy for multiple hematologic malignancies.

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November 16, 2022
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VIDEO: Reviewing uses of JAK2 inhibitors in myelofibrosis

VIDEO: Reviewing uses of JAK2 inhibitors in myelofibrosis

John O. Mascarenhas, MD, spoke with Healio about takeaways from a presentation examining ways to optimize the currently available JAK2 inhibitors for the treatment of myelofibrosis.

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November 11, 2022
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VIDEO: New treatments in myeloproliferative neoplasms signal ‘exciting’ time for field

VIDEO: New treatments in myeloproliferative neoplasms signal ‘exciting’ time for  field

In this video, John O. Mascarenhas, MD, provided an overview of his presentation at 14th International Congress on Myeloproliferative Neoplasms that delved into new treatments, specifically focused on myelofibrosis.

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