Icahn School Of Medicine At Mount Sinai

The combination of olaparib and the investigational ATR inhibitor ceralasertib induced antitumor responses in children and adolescents with DNA repair-deficient tumors, according to phase 1 results of the AcSé-ESMART trial.

The addition of an mRNA-based cancer vaccine to pembrolizumab extended RFS among patients with resected high-risk melanoma, according to study results presented at American Association for Cancer Research Annual Meeting.

LAS VEGAS — Results showed racial and ethnic disparities are more pronounced in the ambulatory care setting compared with the inpatient setting for lumbar surgical care.

NEW ORLEANS — The first U.S. study to examine the link between COVID-19 vaccination and risk for major adverse cardiac events found that vaccination was protective against such events in patients with COVID-19.

SAN FRANCISCO — The addition of atezolizumab to platinum-based chemotherapy failed to significantly improve survival for patients with metastatic urothelial carcinoma, according to a final analysis of the randomized phase 3 IMvigor130 trial.

SAN FRANCISCO — Adjuvant nivolumab improved outcomes compared with placebo for patients with high-risk muscle-invasive urothelial carcinoma, according to study results.

SAN FRANCISCO — Transurethral resection of bladder tumor followed by systemic therapy induced stringently defined clinical complete response among more than 40% of patients with muscle-invasive bladder cancer, according to phase 2 study results.

A short course of itacitinib induced high response rates among patients with low-risk acute graft-versus-host disease, according to study results.

Spontaneous coronary artery dissection is a life-altering event that predominantly affects women, but there is little consensus about how to best diagnose and treat it.

Women who had any of five major adverse pregnancy outcomes had elevated risk for ischemic heart disease for as long as 46 years after delivery, researchers reported in The BMJ.