Ibrutinib-Related Hypertension

Coffee consumption may lower the risk for disease progression and death in patients with advanced or metastatic colorectal cancer, according to recently published study results. It was the top story in hematology/oncology last week.

Ibrutinib — a Bruton tyrosine kinase inhibitor that inhibits B cell-receptor signaling — has demonstrated long-term efficacy as treatment for many mature B-cell malignancies, including chronic lymphocytic leukemia and mantle cell lymphoma.

Ibrutinib, a paradigm-changing drug for the treatment of various blood cancers, appeared to be more closely associated with new or worsened hypertension than previously thought, according to results of a study published in Blood.