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Hypoparathyroidism

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October 23, 2024
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Top in endocrinology: GLP-1s may reduce suicide risk; type 2 diabetes after COVID-19

Adolescents prescribed a GLP-1 receptor agonist for obesity treatment reportedly had lower risk for suicidal thoughts and suicide attempts , according to researchers.

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October 15, 2024
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Parathyroid hormone therapy normalizes calcium for most with hypoparathyroidism

The majority of adults with hypoparathyroidism achieved normal serum calcium levels with palopegteriparatide at 1 year without supplemental vitamin D or calcium, according to data from a phase 3 open-label extension.

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August 12, 2024
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Palopegteriparatide earns FDA approval for treatment of hypoparathyroidism

A parathyroid hormone prodrug developed to treat hypoparathyroidism received FDA approval, according to an industry press release.

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June 07, 2024
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Cognitive decline with hypoparathyroidism linked to changes in brain structure

Adults with hypoparathyroidism experience declines in cognitive function that may be due to structural changes in the brain, according to findings published in the Journal of Bone and Mineral Research.

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May 02, 2024
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FDA fast tracks PTH1 receptor agonist for treatment of hypoparathyroidism

The FDA granted fast track designation for an investigational parathyroid hormone 1 receptor agonist to treat hypoparathyroidism, according to an industry press release.

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April 15, 2024
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The evolving landscape of managing hypoparathyroidism

Approximately 77,000 people in the U.S. have hypoparathyroidism due to absent or subphysiological levels of parathyroid hormone.

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March 15, 2024
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Increased mortality risk for adults who undergo total thyroidectomy for cancer

Adults who develop hypoparathyroidism after a total thyroidectomy have an increased risk for all-cause mortality compared with the general population, but only if the indication for their surgery was cancer, according to study data.

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July 31, 2023
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Fracture risk lower for adults with hypoparathyroidism after thyroidectomy

Adults with postoperative hypoparathyroidism after thyroid cancer are less likely to sustain a fracture compared with those with preserved parathyroid function, according to findings published in the Journal of Bone and Mineral Research.

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May 06, 2023
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PTH therapy cuts need for calcium, vitamin D supplements for most with hypoparathyroidism

SEATTLE — Most adults with hypoparathyroidism no longer needed calcium or vitamin D supplementation after initiating a once-daily active parathyroid hormone drug, according to a speaker.

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May 01, 2023
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FDA declines to OK palopegteriparatide for hypoparathyroidism over manufacturing concerns

The FDA has rejected a new drug application for an agent to treat adults with hypoparathyroidism due to concerns with manufacturing control strategy, according to an industry press release.

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