Hyponatremia

Patients who develop early hyponatremia after starting thiazide diuretics have a higher mortality risk than those with normal sodium levels, according to retrospective study data.

Heat exposure may be linked to increased risk for hyponatremia for older adults, particularly women, according to results of a cross-sectional study of hospitalized adults.

SAN DIEGO — Earlier referral to a nephologist for patients with a hyponatremia electrolyte abnormality may be linked to shorter hospital stays and lower mortality rates, data show.

Results published in the Journal of Bone and Joint Surgery found patients with hyponatremia, a common electrolyte abnormality, are at risk for increased length of stay, complications and nonhome discharge after total joint arthroplasty.

Time-dependent dysnatremias was significantly associated with mortality among patients with chronic kidney disease, according to data published in Kidney Medicine.

Targeted human albumin solution increased serum sodium in hospitalized patients with cirrhosis and hyponatremia, according to prospective data presented at the International Liver Congress.

Abnormal sodium levels are associated with a higher risk for mechanical ventilation and mortality in adults hospitalized with COVID-19, according to data presented at the ENDO annual meeting.

Use of low-sodium dialysate and replacement fluids safely prevented an “overly rapid” correction of plasma sodium in a study of patients with hyponatremia who required continuous renal replacement therapy.

The trajectories of serum sodium levels in hospitalized patients may help predict in-hospital mortality and mortality risk at 1 year, with the highest risk of death found when serum sodium fluctuated “considerably,” according to this study.