Hypercholesterolemia

Two studies presented at the virtual American College of Cardiology Scientific Session highlight new options for LDL cholesterol reduction in patients with homozygous familial hypercholesterolemia.

Among middle-aged Japanese adults, tub bathing was associated with a reduction in CVD and stroke, according to research published in Heart.

Genetic determinants of LDL levels may increase the risk for CVD among patients with hypercholesterolemia, according to a study published in JAMA Cardiology.

The prevalence of obesity and diabetes across 56 European Society of Cardiology member countries has increased two- to threefold in 30 years, hampering efforts to reduce CVD burden, according to the ESC.

The cornerstone of CV prevention is risk assessment because patients at higher risk for atherosclerotic events typically derive a higher absolute benefit from preventive therapies.

A global consortium of representatives from more than 40 countries issued a call to action to address gaps in screening and guideline-based care for patients with familial hypercholesterolemia.

A baseline risk score predicted HF risk in patients with acute leukemia with factors such as left ventricular ejection fraction, anthracycline dose, age and preexisting CVD, according to a study published in JACC: CardioOncology.

In this video exclusive, Abby Fleisch, MD, MPH, attending physician in pediatric endocrinology and diabetes at the Center for Outcomes Research and Evaluation at Maine Medical Center, describes how exposure to common perfluoroalkyl and polyfluoroalkyl substances — better known as the endocrine-disrupting chemicals PFAS — is associated with obesity, diabetes and high cholesterol levels.

Evolocumab in addition to standard of care for the treatment of hypercholesterolemia was shown to have consistent, significant LDL-lowering ability after 5 years of treatment, according to final data from the OSLER-1 trial.

ATLANTA — Similar disparities with regards to CVD are also seen in patients with familial hypercholesterolemia, and more work needs to be done to bring awareness and more research into this area, according to a presentation at the FH Foundation’s FH Global Summit.