Hormone Therapy

Prolonged use of menopausal hormone therapy is associated with high skeletal muscle mass and a low prevalence of sarcopenia among postmenopausal women, according to findings published in Menopause.

Among healthy, postmenopausal women, hormone therapy with oral conjugated equine estrogens — compared with transdermal estradiol or no hormone therapy — may slow the adverse effects of heart fat accumulation on carotid intima-media thickness , according to an analysis of the KEEPS study published in Menopause.

Symptoms associated with menstruation look different for every woman, and surgical options are available for some of the most serious or bothersome. But for those on the cusp of menopause, deciding whether to undergo surgery or even a hysterectomy can be difficult.

Proper care for transgender individuals begins with provider education and recognition that gender incongruence is not primarily a mental health condition, according to a clinical practice update published in The New England Journal of Medicine.

Women aged 50 years and older who had sustained weight loss over more than 8 years demonstrated a decreased risk for breast cancer compared with women whose weight remained stable, according to results of a pooled analysis published in Journal of the National Cancer Institute.

SAN ANTONIO — Two common hormone therapy regimens had opposite long-term effects on breast cancer incidence among postmenopausal women, according to results from two large randomized controlled Women’s Health Initiative trials presented at San Antonio Breast Cancer Symposium.

An analysis of medical records from a large German endocrine clinic suggests more transgender men are seeking gender-affirming treatment, with nearly all individuals reporting an improvement in their overall situation after initiating hormone therapy, according to findings published in Clinical Endocrinology.

The prevalence of type 1 diabetes among transgender and gender-nonconforming youths is more than nine times higher than that of the general population, with researchers exploring the role of increased psychological stress among adolescents with both diagnoses, according to findings from a single-center study published in Pediatric Diabetes.

Chinese girls diagnosed with central precocious puberty achieved greater gains in total height when treated with combination gonadotropin-releasing hormone analogues, or GnRHa, plus recombinant growth hormone therapy, or rhGH, with low predicted adult height and greater bone age predicting greater success with treatment, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Women with fewer total reproductive years may experience elevated risk for atrial fibrillation and subsequent ischemic stroke, according to findings published in Circulation: Arrhythmia and Electrophysiology.