High-Grade Gliomas

A phase 1 trial showed chimeric antigen receptor T-cell therapy may hold promise for the treatment of glioblastoma.

The addition of interferon alfa to temozolomide significantly extended survival among patients with newly diagnosed high-grade gliomas, according to data published in JAMA Network Open.

Use of a modified herpesvirus with and without radiation showed promising efficacy and safety for the treatment of children with recurrent or progressive high-grade glioma, according to results of a phase 1 trial.