Hepatocellular Carcinoma

The combination of cabozantinib and atezolizumab prolonged PFS compared with sorafenib among patients with previously untreated advanced hepatocellular carcinoma, according to topline data released by one of the agent’s manufacturers.

The C-reactive protein and alpha-fetoprotein in immunotherapy score identified patients with favorable hepatocellular carcinoma disease control and survival, according to a study presented at the International Liver Congress.

Treatment with hepatic arterial infusion chemotherapy in combination with sintilimab allowed for surgical resection and produced survival rates similar to lesser advanced hepatocellular carcinoma, according to a presenter at The International Liver Congress.

Ultrasound quality changed between examinations for hepatocellular carcinoma detection in patients with cirrhosis, according to research published in Clinical Gastroenterology and Hepatology.

Hepatic arterial infusion chemotherapy of FOLFOX regimens demonstrated superior efficacy and OS than sorafenib as first-line treatment of advanced hepatocellular carcinoma with a heavy intrahepatic tumor burden.

There are four scenarios in which patients with HCC and extrahepatic disease (EHD) should be considered for locoregional therapy (LRT) in the form of radioembolization or other options (eg, ablation, external radiotherapy).

Liver cancer — the fastest-growing cause of cancer death in the U.S. — has been notoriously difficult to treat.

Nonalcoholic fatty liver disease correlated with a significantly increased risk for developing cancer overall, due to the significant increased incidence in hepatocellular carcinoma, according to study results.

More than one-third of a small cohort patients with early-stage hepatocellular carcinoma achieved at least 50% tumor necrosis following neoadjuvant treatment with cemiplimab, results of a phase 2a trial showed.

Patients with cirrhosis prioritize early-detection over factors like convenience when it comes to hepatocellular carcinoma surveillance, according to study results.