Hematopoietic Stem Cell Transplantation
Fludarabine shortage requires flexibility, alternative approaches for CAR-T and HSCT
For the second time in the last 2 years, a drug related to the administration of cellular therapy — fludarabine — has been placed on the FDA’s drug shortage list.
Cytomegalovirus Management Curbside Consults: Preemptive Therapy Versus Prophylaxis in At-Risk Patients Undergoing HSCT
This activity is supported by an educational grant from Merck & Co., Inc.
Age alone should not be barrier to hematopoietic stem cell transplantation consult
A patient aged 72 years with high-risk myelodysplastic syndrome presents at a community hematology/oncology clinic.
FDA grants priority review to omidubicel for stem cell transplant to treat blood cancers
The FDA granted priority review to omidubicel, an investigational donor-based stem cell therapy for patients with hematologic malignancies undergoing allogeneic hematopoietic stem cell transplantation.
Decitabine ‘better-tolerated alternative’ to chemotherapy for older, fit patients with AML
Older, fit patients with acute myeloid leukemia who received decitabine had transplant and survival rates comparable to those treated with induction chemotherapy but with fewer toxicities, according to results of a randomized phase 3 study.
Triplet induction, autologous HSCT, lenalidomide maintenance extend PFS in multiple myeloma
CHICAGO — Lenalidomide, bortezomib and dexamethasone plus autologous stem cell transplantation and lenalidomide-based maintenance conferred a significant PFS benefit among patients with newly diagnosed multiple myeloma.
FDA grants fast track designation to mocravimod with HSCT for acute myeloid leukemia
The FDA granted fast track designation to mocravimod in combination with allogeneic hematopoietic stem cell transplantation for post-remission therapy of acute myeloid leukemia.
Oncology Nursing Foundation announces mentorship award recipient
Kathleen Shannon Dorcy, PhD, RN, FAAN, received this year’s Connie Henke Yarbro Excellence in Cancer Nursing Mentorship Award.
Early outcomes favorable among transplant recipients whose donors had COVID-19
In the third installment of a three-part video series, Heather Stefanski, MD, PhD, discusses the impact of COVID-19 on the National Marrow Donor Program/Be The Match.
Umbilical cord blood an appropriate stem cell source for certain patients
In the second installment of a three-part video series, Heather Stefanski, MD, PhD, discusses the potential role of umbilical cord blood as a stem cell source.