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Hematopoietic Stem Cell Transplantation

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January 10, 2024
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As CAR-T emerges, stem cell transplants for lymphoma in ‘marked decline’

As CAR-T emerges, stem cell transplants for lymphoma in ‘marked decline’

SAN DIEGO — The volume of hematopoietic stem cell transplantation procedures for advanced diffuse large B-cell lymphoma has declined precipitously since 2019, study results presented at ASH Annual Meeting and Exhibition showed.

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January 06, 2024
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BLOG: Microbiome’s role in outcomes, relapse risk after HSCT or cellular therapy

BLOG: Microbiome’s role in outcomes, relapse risk after HSCT or cellular therapy

The microbiome is linked to myriad processes in human health and disease.

News
November 04, 2023
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BLOG: Preparing HSCT, CAR-T recipients for the respiratory viral season

BLOG: Preparing HSCT, CAR-T recipients for the respiratory viral season

This blog post provides answers to important questions about the upcoming respiratory viral seasons.

News
August 11, 2023
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Gut bacteria diversity affects survival among children who undergo stem cell transplant

Gut bacteria diversity affects survival among children who undergo stem cell transplant

Younger patients with diverse gut microbiota prior to allogeneic hematopoietic stem cell transplantation had a significantly lower risk for death following the procedure than those with low diversity, according to study results.

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June 28, 2023
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Survival rates improve among infants with severe combined immunodeficiency screenings

Survival rates improve among infants with severe combined immunodeficiency screenings

Five-year survival rates among children with severe combined immunodeficiency remained stable at 72% to 73% from 1982 to 2009 before improving to 87% from 2010 to 2018, according to a study published in The Lancet.

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May 13, 2023
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BLOG: GSTA1*B polymorphism may be prognostic for treosulfan-based HCT in beta-thalassemia

BLOG: GSTA1*B polymorphism may be prognostic for treosulfan-based HCT in beta-thalassemia

A treosulfan-based reduced-toxicity conditioning regimen has significantly improved hematopoietic cell transplantation outcomes for patients with high-risk thalassemia major and hematologic malignancies.

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April 05, 2023
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BLOG: Update on double-stranded DNA viruses from Tandem Meetings

BLOG: Update on double-stranded DNA viruses from Tandem Meetings

Reactivation of double-stranded DNA viruses is an important cause of morbidity and mortality after hematopoietic stem cell transplantation.

News
March 07, 2023
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Custom tool sharply reduces errors in stem cell transplant engraftment reporting

Custom tool sharply reduces errors in stem cell transplant engraftment reporting

Time to engraftment after hematopoietic stem cell transplantation is an important outcome that institutions are legally required to report to the Center for International Blood and Marrow Transplant Research.

News
February 12, 2023
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Itacitinib appears effective for acute graft-versus-host disease

Itacitinib appears effective for acute graft-versus-host disease

A short course of itacitinib induced high response rates among patients with low-risk acute graft-versus-host disease, according to study results.

News
January 03, 2023
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Consolidation high-dose chemotherapy plus HSCT extends survival in primary CNS lymphoma

Consolidation high-dose chemotherapy plus HSCT extends survival in primary CNS lymphoma

NEW ORLEANS — Consolidation therapy with high-dose chemotherapy followed by hematopoietic stem cell transplant significantly prolonged PFS among adults with primary central nervous system lymphoma, according to study results.

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