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Heart Failure

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March 26, 2021
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AF confers elevated mortality risk in hypertrophic cardiomyopathy

AF confers elevated mortality risk in hypertrophic cardiomyopathy

Incident atrial fibrillation in a cohort of patients with hypertrophic cardiomyopathy, or HCM, was associated with elevated risk for cardiac death, according to research published in EClinicalMedicine.

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March 24, 2021
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Beta-blockers not tied to depression; sleep disorder link less clear

Beta-blockers not tied to depression; sleep disorder link less clear

Beta-blockers were not associated with depression and other psychiatric adverse events, although they may have a relationship with sleep disorders, according to a meta-analysis.

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March 23, 2021
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Black patients consistently underrepresented in pivotal CVD trials

Black patients consistently underrepresented in pivotal CVD trials

In contrast to their prevalence in the overall disease population, Black individuals were considerably underrepresented in trials that affirmed the FDA’s approval of 24 CVD treatments, researchers reported.

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March 22, 2021
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Patients with STEMI, no modifiable CV risk factors at elevated mortality risk

Patients with STEMI, no modifiable CV risk factors at elevated mortality risk

Patients presenting with STEMI who do not have standard modifiable CV risk factors are at elevated risk for all-cause mortality, according to results published in The Lancet.

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March 20, 2021
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AHA, ABC announce data challenge to assess social determinants of health, HF relationship

AHA, ABC announce data challenge to assess social determinants of health, HF relationship

The American Heart Association and Association of Black Cardiologists launched a joint data challenge to better understand the effects of social and structural determinants of health in HF.

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March 19, 2021
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Mineralocorticoid receptor antagonist use does not affect empagliflozin HF, renal benefits

Mineralocorticoid receptor antagonist use does not affect empagliflozin HF, renal benefits

The use of mineralocorticoid receptor antagonists did not influence the ability of empagliflozin to reduce adverse HF and renal outcomes, according to data from EMPEROR-Reduced published in the Journal of the American College of Cardiology.

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March 18, 2021
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Transthyretin cardiac amyloidosis: A guide on tafamidis use, navigating medication access

Transthyretin cardiac amyloidosis: A guide on tafamidis use, navigating medication access

Amyloidosis is a disease in which specific precursor proteins misfold into beta-pleated sheets. Misfolded proteins adhere to form oligomers resulting in insoluble amyloid fibrils that deposit into tissue.

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March 18, 2021
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In older patients with HFpEF, worse outcomes for women than men

In older patients with HFpEF, worse outcomes for women than men

Female sex was independently associated with diastolic dysfunction and worse clinical outcomes in a cohort of older patients with HF with preserved ejection fraction, researchers reported.

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March 17, 2021
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Subclinical systolic impairment may indicate future HF risk in older patients

Subclinical systolic impairment may indicate future HF risk in older patients

Subclinical impairments in left ventricular systolic function were associated with risk for future incident HF among older adults, according to research published in JAMA Cardiology.

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March 12, 2021
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Mortality risk lower for patients with mild HF stabilized early with CRT

Mortality risk lower for patients with mild HF stabilized early with CRT

Patients with mild HF on cardiac resynchronization therapy had lower risk for mortality if they improved or stabilized on CRT compared with if they worsened, researchers reported.

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