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Heart Failure

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May 21, 2021
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Secondhand smoke tied to elevated odds of HF

Secondhand smoke tied to elevated odds of HF

Secondhand smoke exposure was associated with elevated odds of HF, especially in men, according to a presentation at the American College of Cardiology Scientific Session.

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May 19, 2021
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GALACTIC-HF: Benefit of omecamtiv mecarbil strongest at lowest EF

GALACTIC-HF: Benefit of omecamtiv mecarbil strongest at lowest EF

The treatment effect of omecamtiv mecarbil in patients with HF rose as left ventricular ejection fraction declined, according to new data from the GALACTIC-HF trial presented at the American College of Cardiology Scientific Session.

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May 19, 2021
10 min read
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SGLT2 inhibitors now ‘pillars of care’ for HF

SGLT2 inhibitors now ‘pillars of care’ for HF

HF and type 2 diabetes are intertwined. Their shared pathophysiology can accelerate debilitating outcomes for patients that clinicians struggle to prevent and treat.

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May 19, 2021
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DETO2X-AMI

DETO2X-AMI

Efficacy of oxygen therapy in patients with acute MI according to sex.

News
May 18, 2021
3 min read
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In HF, AF, rhythm control with ablation not superior to rate control; trial underpowered

In HF, AF, rhythm control with ablation not superior to rate control; trial underpowered

Ablation-based rhythm control for patients with HF and atrial fibrillation did not significantly reduce all-cause death and HF events compared with a rate-control strategy, a speaker reported.

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May 18, 2021
11 min read
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Diabetes drugs now ‘pillars of care’ for heart failure

Diabetes drugs now ‘pillars of care’ for heart failure

Heart failure and type 2 diabetes are exquisitely intertwined. Their shared pathophysiology can accelerate debilitating outcomes for patients that clinicians struggle to prevent and treat.

News
May 17, 2021
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PIROUETTE: Pirfenidone reduces myocardial fibrosis in patients with HFpEF

PIROUETTE: Pirfenidone reduces myocardial fibrosis in patients with HFpEF

In patients with HF with preserved ejection fraction, pirfenidone was associated with reduction in myocardial fibrosis compared with placebo, according to a presentation at the American College of Cardiology Scientific Session.

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May 17, 2021
2 min read
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Hospital, post-discharge quality improvement intervention failed to improve HFrEF outcomes

Hospital, post-discharge quality improvement intervention failed to improve HFrEF outcomes

A hospital and post-discharge quality improvement intervention did not improve rehospitalization or survival in patients with HF with reduced ejection fraction beyond existing quality improvement programs, researchers reported.

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May 17, 2021
4 min read
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Sotagliflozin shows ‘consistent’ HFpEF benefit in new SCORED/SOLOIST analysis

Sotagliflozin shows ‘consistent’ HFpEF benefit in new SCORED/SOLOIST analysis

The dual SGLT inhibitor sotagliflozin reduced risk for total CV death, HF hospitalization and urgent HF visits across the full range of ejection fraction, including preserved EF, data from a pooled analysis showed.

News
May 17, 2021
2 min read
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Sacubitril/valsartan not superior to valsartan alone in advanced HFrEF: LIFE

Sacubitril/valsartan not superior to valsartan alone in advanced HFrEF: LIFE

In patients with advanced HF, sacubitril/valsartan was not superior to valsartan for reducing N-terminal pro-B natriuretic peptide levels at 24 weeks, according to the results of the LIFE trial.

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