Heart Failure

Adults with heart failure with reduced ejection fraction derived similar benefits with empagliflozin regardless of other disease-modifying heart failure therapies prescribed at baseline, post hoc analysis of the EMPEROR-Reduced trial show.

Individuals with HIV were at elevated risk for developing HF compared with individuals without HIV, according to new research published in Mayo Clinic Proceedings.

Hypertrophic cardiomyopathy is the most common genetic heart disease, with prevalence estimates from one in 200 to one in 500. However, the true prevalence is poorly understood due to likely underdiagnosis.

Empagliflozin (Jardiance, Boehringer Ingelheim/Eli Lilly) vs. placebo in patients hospitalized with acute HF.

Cytokinetics announced that the FDA has granted breakthrough therapy designation for aficamten, a next-generation cardiac myosin inhibitor, for the treatment of symptomatic obstructive hypertrophic cardiomyopathy.

Mineralocorticoid receptor antagonists, particularly the most recently approved agent finerenone, should play a “central role” in the treatment of diabetic kidney disease and its related cardiovascular consequences, according to a speaker.

Data that indicated better outcomes among some patients with cardiac arrest who had epinephrine administered fewer than 5 minutes after their first defibrillation was the top story in cardiology last week.

Patients admitted with HF with amyloidosis had a higher 30-day, all-cause readmission rate and longer hospital stay vs. HF patients without amyloidosis, study data presented at the American Heart Association Scientific Sessions show.

Vitamin D deficiency status was linked to increased length of stay, but lower in-hospital mortality, in patients hospitalized with acute HF, according to a presentation from the American Heart Association Scientific Sessions.

Higher BMI was linked to greater risk for HF-related hospitalizations in patients with HF with preserved ejection fraction, regardless of age, sex and diabetes status, a speaker reported.