Head And Neck Cancer
Amid questions about cost and access, proton therapy set for ‘big moment of change’
More than 3 decades after receiving FDA approval, proton beam radiation therapy has failed to find a footing as a go-to treatment for many cancers in the United States.
Rural residents with head and neck cancer at significantly higher risk for suicide
Patients with head and neck cancer who reside in rural areas appeared five times more likely to commit suicide than the general population, according to study results published in JAMA Otolaryngology-Head & Neck Surgery.
Delaware, a state of firsts, sets new example with cancer treatment program
Delaware was named after the Delaware River, which in turn derived its name from Thomas West, Lord De La Warr, the English governor of Virginia who first explored the Delaware Bay in 1611.
Trial of nivolumab plus ipilimumab for first-line HNSCC misses primary endpoints
A phase 3 trial of nivolumab plus ipilimumab vs. the EXTREME regimen as first-line treatment of advanced squamous cell carcinoma of the head and neck failed to meet its primary endpoints of OS, according to a company-issued press release.
Blood test may detect treatment failure earlier in oropharynx squamous cell cancer subset
A novel noninvasive droplet digital polymerase chain reaction-based assay predicted treatment response months before standard imaging scans among a cohort of patients with metastatic HPV-associated oropharynx squamous cell carcinoma.
Two neoadjuvant cycles of pembrolizumab safe, effective in head and neck cancer subset
Two cycles of neoadjuvant pembrolizumab appeared safe and did not delay surgery among a cohort of patients with surgically resectable, locally advanced, HPV-negative head and neck squamous cell carcinoma, according to phase 2 study results.
Toripalimab plus first-line chemotherapy extends PFS in advanced nasopharyngeal carcinoma
Adding toripalimab to gemcitabine-cisplatin chemotherapy significantly improved PFS and overall response rates and induced longer-lasting responses than chemotherapy alone as first-line therapy for advanced nasopharyngeal carcinoma.
Increased epigenetic age acceleration observed among patients with head and neck cancer
Patients with head and neck cancer experienced an increase in epigenetic age acceleration, especially directly after treatment, which appeared associated with greater fatigue and inflammation, according to a study in Cancer.
FDA grants fast track designation to CAR T-cell therapy for thyroid cancer
The FDA granted fast track designation to AIC100, a chimeric antigen receptor T-cell therapy, for the treatment of anaplastic thyroid cancer and refractory poorly differentiated thyroid cancer, according to the agent’s manufacturer.
Cervical cancer incidence declines as rates of other HPV-associated cancers rise
Incidence of cervical cancer declined as rates of other HPV-associated cancers increased significantly in the U.S. from 2001 to 2017, according to a population-based study of trends presented during the virtual ASCO Annual Meeting.