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Gynecologic Cancer

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January 12, 2022
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Report: Lung cancer survival improves, progress stagnates in breast, prostate cancers

Report: Lung cancer survival improves, progress stagnates in breast, prostate cancers

An increasing percentage of lung cancer cases are being diagnosed at an earlier stage, according to a new report from American Cancer Society.

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December 22, 2021
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FDA clears IND application for allogeneic CAR-T to treat certain solid tumors

FDA clears IND application for allogeneic CAR-T to treat certain solid tumors

The FDA cleared an investigational new drug application for P-MUC1C-ALLO1, a chimeric antigen receptor T-cell therapy designed to treat adults with locally advanced or metastatic epithelial-derived solid tumors.

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December 22, 2021
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New NASA radiation exposure limit would bring equality to female, male astronauts

New NASA radiation exposure limit would bring equality to female, male astronauts

A committee of experts from science, medicine and academia, among other fields, has recommended NASA proceed with a proposal for a universal, career-long radiation dose limit for all astronauts.

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December 08, 2021
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Tamoxifen-induced PI3 kinase pathway activation may increase uterine cancer risk

Tamoxifen-induced PI3 kinase pathway activation may increase uterine cancer risk

Patients with breast cancer who developed tamoxifen-associated uterine cancer had fewer phosphatidylinositol 3-kinase pathway mutations than those with de novo cases, according to results presented at San Antonio Breast Cancer Symposium.

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December 02, 2021
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Cytoreductive surgery before chemotherapy benefits women with recurrent ovarian cancer

Cytoreductive surgery before chemotherapy benefits women with recurrent ovarian cancer

Cytoreductive surgery before chemotherapy led to significant and clinically meaningful OS and PFS benefits for women with recurrent ovarian cancer, according to a phase 3 study published in The New England Journal of Medicine.

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December 01, 2021
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Mirvetuximab soravtansine active in previously treated ovarian cancer

Mirvetuximab soravtansine active in previously treated ovarian cancer

Mirvetuximab soravtansine induced confirmed objective response in about one-third of women with folate receptor alpha-high platinum-resistant ovarian cancer who previously received bevacizumab, according to the agent’s manufacturer.

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November 30, 2021
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FDA approves Cytalux to identify ovarian cancer lesions during surgery

FDA approves Cytalux to identify ovarian cancer lesions during surgery

The FDA approved the imaging drug pafolacianine to help surgeons identify ovarian cancer lesions.

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November 27, 2021
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Roswell Park appoints chair in gynecologic oncology

Roswell Park appoints chair in gynecologic oncology

Emese Zsiros, MD, PhD, has been promoted to lead the department of gynecologic oncology at Roswell Park Comprehensive Cancer Center.

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November 18, 2021
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Most therapies tested in phase 3 cancer trials fail to confer meaningful survival benefit

Most therapies tested in phase 3 cancer trials fail to confer meaningful survival benefit

More than 80% of therapies tested in phase 3 oncology trials did not demonstrate clinically meaningful benefit in extending survival, according to results of a study published in JNCCN — Journal of the National Comprehensive Cancer Network.

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November 02, 2021
4 min read
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Neoadjuvant chemotherapy may be optimal first-line treatment in advanced ovarian cancer

Neoadjuvant chemotherapy may be optimal first-line treatment in advanced ovarian cancer

Increased use of neoadjuvant chemotherapy appeared associated with improvements in short-term mortality without sacrificing long-term survival in ovarian cancer, according to a comparative effectiveness research study in JAMA Oncology.

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